Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | EDNRB | P24530 | 3/20 | 0.37 |
| ▸ | EDNRA | P25101 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21662246 | 0.90 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1EDNRBEDNRAMEN1 | |
| SCHEMBL21662194 | 0.90 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1EDNRBEDNRAATM | |
| SCHEMBL23956032 | 0.89 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1EDNRBEDNRAMEN1 | |
| SCHEMBL21662334 | 0.86 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MEN1NPC1LMNA | |
| SCHEMBL19781085 | 0.84 | MAP1LC3B (0.44) | ALDH1A1L3MBTL1MEN1NPC1LMNA | |
| SCHEMBL21662337 | 0.84 | L3MBTL1 (0.43) | ALDH1A1L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL21661978 | 0.81 | L3MBTL1 (0.33) | L3MBTL1EDNRBEDNRATHRBMAP1LC3B | |
| SCHEMBL23956059 | 0.80 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1EDNRBEDNRAATM | |
| SCHEMBL21662331 | 0.80 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1MEN1NPC1RAB9A | |
| SCHEMBL21662145 | 0.78 | PARP10 (0.38) | L3MBTL1EDNRBEDNRAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | PAH, ALG3, DDC | ALDH1A1 666/4885L3MBTL1 3034/4885EDNRB 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.