Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21662341 | 0.85 | TNKS2 (0.36) | TNKSTNKS2PARP3 | |
| SCHEMBL21662168 | 0.73 | PDK2 (0.31) | — | |
| SCHEMBL21662339 | 0.71 | CFTR (0.40) | PARP3 | |
| SCHEMBL21662332 | 0.68 | L3MBTL1 (0.36) | — | |
| SCHEMBL21661983 | 0.64 | ACHE (0.31) | — | |
| SCHEMBL21662201 | 0.63 | BRD4 (0.38) | — | |
| SCHEMBL21662333 | 0.60 | L3MBTL1 (0.38) | TNKSTNKS2PARP3 | |
| SCHEMBL14457823 | 0.59 | TNKS2 (0.36) | TNKSTNKS2PARP3 | |
| SCHEMBL370544 | 0.59 | ALDH1A1 (0.58) | TNKSTNKS2PARP3 | |
| SCHEMBL10069663 | 0.56 | TNKS2 (0.47) | TNKSTNKS2PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601257-B1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-20200039903-A1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | PAH, ALG3, DDC | TNKS 2197/4885TNKS2 2469/4885PARP3 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.