Sugi Predict

Sugi Predict / Compounds / SCHEMBL21664216

SCHEMBL21664216

SCHEMBL21664216

C[C@@H]1NC(=O)CC[C@@H](C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MC3R P41968 9/20 0.52
▸ MC4R P32245 8/20 0.52
▸ MC5R P33032 7/20 0.52
▸ TSLP Q969D9 4/20 0.50
▸ HDAC3 O15379 1/20 0.49
▸ HDAC4 P56524 1/20 0.49
▸ HDAC1 Q13547 1/20 0.49
▸ HDAC7 Q8WUI4 1/20 0.49
▸ HDAC2 Q92769 1/20 0.49
▸ HDAC10 Q969S8 1/20 0.49
▸ HDAC11 Q96DB2 1/20 0.49
▸ HDAC8 Q9BY41 1/20 0.49
▸ HDAC6 Q9UBN7 1/20 0.49
▸ HDAC9 Q9UKV0 1/20 0.49
▸ HDAC5 Q9UQL6 1/20 0.49
▸ ITGB3 P05106 1/20 0.49
▸ ITGAV P06756 1/20 0.49
▸ ITGA2B P08514 1/20 0.49
▸ F12 P00748 2/20 0.46
▸ MC1R Q01726 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21689230 0.94 TSLP (0.48) MC3RMC4RMC5RTSLPHDAC3
SCHEMBL21664060 0.92 TSLP (0.53) MC3RMC4RMC5RTSLPHDAC3
SCHEMBL21664161 0.89 MMP2 (0.49) MC3RMC4RMC5RTSLPHDAC3
SCHEMBL21664068 0.85 TSLP (0.56) MC3RMC5RTSLPHDAC3HDAC4
SCHEMBL13478156 0.82 OPRM1 (0.61) MC3RMC4RMC5RTSLPHDAC3
SCHEMBL12706706 0.82 OPRM1 (0.61) MC3RMC4RMC5RTSLPHDAC3
SCHEMBL13739916 0.82 OPRM1 (0.61) MC3RMC4RMC5RTSLPHDAC3
SCHEMBL30787065 0.81 HDAC3 (0.56) MC3RMC4RMC5RHDAC3HDAC4
SCHEMBL12971657 0.80 TSLP (0.48) MC3RMC4RMC5RTSLPHDAC3
SCHEMBL13121285 0.80 TSLP (0.48) MC3RMC4RMC5RTSLPHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 — — US disclosed
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORPORATION (JP) 2020-02-06 — — US disclosed
EP-3604326-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM Corporation (JP) 2020-02-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND VIP, NPPA, NGLY1 MC3R 1620/4885MC4R 849/4885MC5R 1153/4885
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 MC3R 1620/4885MC4R 849/4885MC5R 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.