SCHEMBL216654

SCHEMBL216654

CCCc1cccc(O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.67
DRD3 P35462 5/20 0.67
DRD1 P21728 2/20 0.67
DRD4 P21917 1/20 0.67
DRD5 P21918 1/20 0.67
TAAR1 Q96RJ0 1/20 0.63
CHRM2 P08172 1/20 0.62
CHRM1 P11229 1/20 0.62
CHRM3 P20309 1/20 0.62
OPRK1 P41145 5/20 0.61
OPRM1 P35372 4/20 0.61
OPRD1 P41143 4/20 0.61
ENPP2 Q13822 1/20 0.56
GABRA1 P14867 1/20 0.55
GABRG2 P18507 1/20 0.55
GABRB3 P28472 1/20 0.55
GABRA3 P34903 1/20 0.55
GABRA2 P47869 1/20 0.55
GABRB2 P47870 1/20 0.55
CNR1 P21554 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29473925 1.00 DRD2 (0.67) DRD2DRD3DRD1DRD4DRD5
Phenol SCHEMBL1236990 0.94 OPRK1 (0.65) DRD2DRD3DRD1DRD4DRD5
SCHEMBL2368581 0.92 DRD2 (0.59) DRD2DRD3DRD1DRD4DRD5
Bicarbonate SCHEMBL6270245 0.92 DRD2 (0.59) DRD2DRD3DRD1DRD4DRD5
SCHEMBL29558042 0.87 DRD2 (0.63) DRD2DRD3DRD1DRD4DRD5
SCHEMBL295433 0.87 DRD2 (0.63) DRD2DRD3DRD1DRD4DRD5
SCHEMBL8512566 0.86 DRD2 (0.53) DRD2DRD3DRD1DRD4DRD5
SCHEMBL723832 0.85 DRD2 (0.74) DRD2DRD3DRD1DRD4DRD5
SCHEMBL647539 0.85 PTGS2 (0.64) DRD2DRD3DRD1DRD4DRD5
SCHEMBL3358472 0.84 PTGS2 (0.66) DRD2DRD3DRD1DRD4DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2107 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037020-A Supported catalyst, preparation method thereof and application thereof in olefin polymerization 中国石油化工股份有限公司 2026-05-15 CN claimed
CN-122011307-A Method for synthesizing phenolic resin from 2,4/2, 5-methyl ethyl phenol 煤炭科学技术研究院有限公司 2026-05-12 CN claimed
CN-122011306-A Method for synthesizing phenolic resin from mixed phenol containing 2,4, 6-tricresyl 煤炭科学技术研究院有限公司 2026-05-12 CN claimed
US-20250134790-A1 ANTIMICROBIAL COMPOSITIONS FIRMENICH SA (CH) 2025-05-01 US claimed
CN-113396171-B Process for producing polyphenol derivative, and resin composition containing polyphenol derivative 出光兴产株式会社 2025-03-28 CN claimed
CN-119486703-A Fragrance composition with lasting fragrance appearance 弗门尼舍有限公司 2025-02-18 CN claimed
US-12133544-B2 Composition comprising taste modulation compounds, their use and foodstuff comprising them V. MANE FILS (FR) 2024-11-05 US claimed
US-20240253988-A1 PROCESS FOR THE PRODUCTION OF HYDROGEN PEROXIDE ARKEMA FRANCE (FR) 2024-08-01 US claimed
EP-4387583-A1 ANTIMICROBIAL COMPOSITIONS Firmenich SA (CH) 2024-06-26 EP claimed
US-12016358-B2 Composition comprising taste modulation compounds, their use and foodstuff comprising them V. MANE FILS (FR) 2024-06-25 US claimed
US-6846847-B2 Biocidal agents and methods of use HOLWERDA COMMUNITY TRUST 2005-01-25 US claimed
US-20040024020-A1 Biocidal agents and methods of use MYRMECOL 2004-02-05 US claimed
US-20020182298-A1 Free alkylphenol flavor additives WHOLE FLAVORS LLC (US) 2002-12-05 US claimed
EP-1189520-A1 FREE ALKYLPHENOL FLAVOR ADDITIVES Whole Flavors LLC (US) 2002-03-27 EP claimed
US-6291392-B2 Catalysts containing a platinum group metal and produced in a sol-gel method, as well as a method for producing diarylcarbonates BAYER AKTIENGESELLSCHAFT (DE) 2001-09-18 US claimed
WO-2001001796-A1 FREE ALKYLPHENOL FLAVOR ADDITIVES WHOLE FLAVORS, LLC (US) 2001-01-11 WO claimed
EP-0922050-A1 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 1999-06-16 EP claimed
WO-1997042205-A1 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 1997-11-13 WO claimed
US-5446109-A Melt reacting while heating in presence of a phenolic compound TEIJIN LIMITED (JP) 1995-08-29 US claimed
US-4242277-A STABILIZATION OF NITROUS ACID BY AN ORGANIC ACID AND ANOTHER ACID TO OBTAIN BENZOQUINONE OXIMES MITSUBISHI PETROCHEMICAL COMPANY, LIMITED (JP) 1980-12-30 US claimed