SCHEMBL723832

SCHEMBL723832

Oc1cccc(CCc2cccc(O)c2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.74
DRD1 P21728 2/20 0.74
TAAR1 Q96RJ0 1/20 0.74
CHRM2 P08172 1/20 0.65
CHRM1 P11229 1/20 0.65
CHRM3 P20309 1/20 0.65
ENPP2 Q13822 1/20 0.65
OPRK1 P41145 4/20 0.63
GABRA1 P14867 1/20 0.62
GABRG2 P18507 1/20 0.62
GABRB3 P28472 1/20 0.62
GABRA3 P34903 1/20 0.62
GABRA2 P47869 1/20 0.62
GABRB2 P47870 1/20 0.62
CALM1 P0DP23 1/20 0.60
MIF P14174 1/20 0.59
DRD4 P21917 1/20 0.59
DRD5 P21918 1/20 0.59
DRD3 P35462 1/20 0.59
CYP3A4 P08684 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23754287 0.93 GABRA1 (0.67) DRD2DRD1TAAR1CHRM2CHRM1
3-Phenethylphenol SCHEMBL717571 0.93 OPRK1 (0.74) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL8947211 0.93 GABRA1 (0.67) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL29449650 0.93 GABRA1 (0.67) DRD2DRD1TAAR1CHRM2CHRM1
Lunularin SCHEMBL717118 0.91 LTA4H (0.64) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL28368586 0.90 DRD2 (0.68) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL11232474 0.90 DRD2 (0.68) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL31674607 0.90 DRD2 (0.68) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL6356100 0.89 DRD2 (0.61) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL8398287 0.87 MGLL (0.68) DRD2DRD1TAAR1CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108914584-B Manufacturing method of polishing cloth 无锡旺绿鸿纺织品有限公司 2021-05-18 CN claimed
EP-0000097-B1 POLYARYLENE ESTERS MOULDING COMPOSITIONS, PROCESS FOR THEIR PREPARATION AND SHAPED ARTICLES THEREFROM MONSANTO COMPANY (US) 1981-02-11 EP claimed
EP-0000097-A1 Polyarylene esters moulding compositions, process for their preparation and shaped articles therefrom MONSANTO COMPANY (US) 1978-12-20 EP claimed
US-4127557-A PHENOL-TETRACHLOROETHANE SOLVENT MONSANTO COMPANY (US) 1978-11-28 US claimed
US-4115357-A MOLDING RESINS, FIBERS, COATINGS MONSANTO COMPANY (US) 1978-09-19 US claimed
US-4102864-A SOLVENT AND CRACK RESISTANCE MONSANTO COMPANY (US) 1978-07-25 US claimed
US-4101517-A POTASSIUM COMPOUND AS CATALYST MONSANTO COMPANY (US) 1978-07-18 US claimed
US-20200375949-A1 BISPHENOL COMPOUNDS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2020-12-03 US disclosed
US-20200375949-A1 BISPHENOL COMPOUNDS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2020-12-03 US disclosed
WO-2019104153-A1 BISPHENOL COMPOUNDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2019-05-31 WO disclosed
WO-2019104153-A1 BISPHENOL COMPOUNDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2019-05-31 WO disclosed
WO-2018090805-A1 SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS HONG KONG BAPTIST UNIVERSITY (CN) 2018-05-24 WO disclosed
US-8541625-B2 Cyclopropenones and the photochemical generation of cyclic alkynes therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2013-09-24 US disclosed
US-20120053299-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2012-03-01 US disclosed
US-20100210854-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2010-08-19 US disclosed
EP-0000097-B1 POLYARYLENE ESTERS MOULDING COMPOSITIONS, PROCESS FOR THEIR PREPARATION AND SHAPED ARTICLES THEREFROM MONSANTO COMPANY (US) 1981-02-11 EP disclosed
US-4199493-A REINFORCING AGENT AND THERMOPLASTIC VINYL ADDITION POLYMER MONSANTO COMPANY (US) 1980-04-22 US disclosed
US-4127557-A PHENOL-TETRACHLOROETHANE SOLVENT MONSANTO COMPANY (US) 1978-11-28 US disclosed
US-4115357-A MOLDING RESINS, FIBERS, COATINGS MONSANTO COMPANY (US) 1978-09-19 US disclosed
US-4101517-A POTASSIUM COMPOUND AS CATALYST MONSANTO COMPANY (US) 1978-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200375949-A1 BISPHENOL COMPOUNDS RPP30, RPS10, RPS20 DRD2 2596/4885DRD1 1407/4885TAAR1 4418/4885
US-20120053299-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom WEE1, WEE2, MPI DRD2 2357/4885DRD1 2325/4885TAAR1 3922/4885
US-20100210854-A1 Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom WEE1, WEE2, MPI DRD2 2357/4885DRD1 2325/4885TAAR1 3922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.