Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996045 | 0.67 | CA12 (0.66) | KDM4EGAATSHRALDH1A1RAB9A | |
| SCHEMBL4787921 | 0.67 | ALDH1A1 (0.44) | TSHRPOLBALDH1A1PKMLMNA | |
| SCHEMBL18255787 | 0.66 | TTR (0.57) | KDM4EALDH1A1RAB9AHPGDLMNA | |
| SCHEMBL3694807 | 0.66 | TSHR (0.53) | KDM4EGAATSHRPOLBALDH1A1 | |
| SCHEMBL28478921 | 0.65 | ALOX15 (0.61) | KDM4EGAATSHRPOLBALDH1A1 | |
| SCHEMBL4861464 | 0.65 | ALDH1A1 (0.41) | KDM4EGAATSHRALDH1A1ALOX12 | |
| SCHEMBL1278441 | 0.64 | CA12 (0.41) | KDM4EGAATSHRALDH1A1HPGD | |
| SCHEMBL5248806 | 0.64 | TSHR (0.63) | KDM4EGAATSHRPOLBALDH1A1 | |
| SCHEMBL28391542 | 0.64 | CA12 (0.59) | KDM4EGAATSHRALDH1A1RAB9A | |
| SCHEMBL830006 | 0.64 | TSHR (0.63) | KDM4EGAATSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |