Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152871 | 0.68 | ALDH1A1 (0.78) | ALDH1A1LMNAHPGDTSHRTP53 | |
| SCHEMBL7546526 | 0.65 | GAA (0.38) | ALDH1A1LMNAHPGDTP53KDM4E | |
| SCHEMBL21668045 | 0.65 | KDM4E (0.42) | ALDH1A1LMNAHPGDTSHRHSD17B10 | |
| SCHEMBL29483354 | 0.59 | LMNA (0.45) | ALDH1A1LMNAHPGDTSHRTP53 | |
| Hexane SCHEMBL27932185 | 0.58 | MEN1 (0.49) | ALDH1A1LMNATSHRHSD17B10KDM4E | |
| SCHEMBL15141713 | 0.57 | TSHR (0.40) | ALDH1A1TSHRGAA | |
| SCHEMBL15142530 | 0.57 | TSHR (0.40) | ALDH1A1TSHRGAA | |
| Hexane SCHEMBL57827 | 0.56 | ALDH1A1 (0.78) | ALDH1A1LMNATSHRHSD17B10GAA | |
| Hexane SCHEMBL547747 | 0.56 | ALDH1A1 (0.78) | ALDH1A1LMNATSHRHSD17B10GAA | |
| Hexane SCHEMBL301207 | 0.56 | ALDH1A1 (0.78) | ALDH1A1LMNATSHRHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008111794-A1 | 4-METHYLIMIDAZOL-5-YLCARBONYLGUANIDINE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF THE ISCHEMIC HEART DISEASES CONTAINING THE SAME AS AN ACTIVE INGREDIENT | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-09-18 | — | — | WO | disclosed |