Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21668591 | 0.89 | CDK2 (0.40) | CDK2ABCG2CDK1KDM4EAPP | |
| SCHEMBL22789466 | 0.81 | APP (0.39) | CDK2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23473355 | 0.74 | ALDH1A1 (0.35) | CDK2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23473389 | 0.74 | CDK2 (0.44) | CDK2ABCG2CDK1KDM4EALDH1A1 | |
| SCHEMBL21647177 | 0.73 | TERT (0.55) | KDM4EALDH1A1HPGDHSD17B10USP8 | |
| SCHEMBL22772252 | 0.72 | TERT (0.42) | KDM4EALDH1A1HPGDHSD17B10USP8 | |
| SCHEMBL21668590 | 0.71 | CDK2 (0.54) | CDK2ABCG2CDK1KDM4EALDH1A1 | |
| SCHEMBL23473424 | 0.69 | USP8 (0.56) | KDM4EALDH1A1HPGDHSD17B10USP8 | |
| SCHEMBL27629259 | 0.66 | KDM4E (0.46) | KDM4EALDH1A1 | |
| SCHEMBL21668603 | 0.65 | ABCG2 (0.49) | CDK2ABCG2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831821-A1 | COMPOUND FOR TREATING NERVOUS SYSTEM DISEASES AND USE THEREOF | Shaanxi Micot Technology Limited Company (CN) | 2021-06-09 | — | — | EP | disclosed |