SCHEMBL21669643

SCHEMBL21669643

CCS(=O)(=O)CCNC(C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
GRIA1 P42261 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16858303 0.79
SCHEMBL14097301 0.77 NLRP3 (0.33) GRIA1
SCHEMBL6969058 0.75 LMNA (0.36) GRIA1
SCHEMBL25589839 0.75 GRIA1 (0.34) GRIA1
SCHEMBL6494923 0.75 CA1 (0.31) GRIA1
SCHEMBL20076074 0.75 TSHR (0.36)
SCHEMBL28911775 0.73 BBOX1 (0.46)
SCHEMBL24259785 0.73 KMT2A (0.37)
SCHEMBL26724609 0.73 CA1 (0.44) GRIA1
SCHEMBL7049896 0.73 CA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078189-B2 Pharmaceutical compounds ReViral Limited (GB) 2021-08-03 US disclosed
US-20200172515-A1 PHARMACEUTICAL COMPOUNDS SILICON VALLEY BANK 2020-06-04 US disclosed
US-20200039943-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200039943-A1 COMPOUNDS, DEVICES, AND USES THEREOF SLC10A1, SLCO1B3, SLC5A1 SLC6A2 61/4885SLC6A4 204/4885SLC6A3 130/4885
US-11078189-B2 Pharmaceutical compounds HRH4, CHRM5, CHRM1 SLC6A2 1482/4885SLC6A4 2486/4885SLC6A3 2412/4885
US-20200172515-A1 PHARMACEUTICAL COMPOUNDS HRH4, CHRM5, CHRM1 SLC6A2 1482/4885SLC6A4 2486/4885SLC6A3 2412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.