SCHEMBL21670387

SCHEMBL21670387

CC(C)Oc1ccc(O)cc1.CC(C)Oc1ccccc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 1/20 0.46
KMT2A Q03164 4/20 0.45
MEN1 O00255 2/20 0.45
MITF O75030 1/20 0.45
TP53 P04637 2/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TSHR P16473 1/20 0.44
IRAK4 Q9NWZ3 2/20 0.42
PARP10 Q53GL7 1/20 0.41
ALDH1A1 P00352 3/20 0.40
ACHE P22303 1/20 0.40
GAA P10253 2/20 0.40
LMNA P02545 1/20 0.40
LTA4H P09960 1/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
ALDH1A3 P47895 1/20 0.39
POLB P06746 1/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29737595 0.87 TP53 (0.56) TP53CA1CA2TSHRIRAK4
SCHEMBL104203 0.87 TP53 (0.56) TP53CA1CA2TSHRIRAK4
SCHEMBL28485 0.82 KMT2A (0.56) KMT2AMEN1MITFCA1CA2
SCHEMBL9658604 0.80 LTA4H (0.50) PNLIPKMT2AMEN1MITFIRAK4
SCHEMBL20357567 0.79 CYP1A2 (0.59) KMT2ATSHRALDH1A1GAALMNA
SCHEMBL4962026 0.77 ALDH1A1 (0.48) PNLIPKMT2AIRAK4PARP10ALDH1A1
Phenol SCHEMBL28170152 0.77 KMT2A (0.50) KMT2AMEN1MITFTP53CA1
SCHEMBL863444 0.77 ESR2 (0.58) KMT2AMEN1MITFTP53TSHR
SCHEMBL1619622 0.77 KMT2A (0.64) PNLIPKMT2AMEN1PARP10LTA4H
Carbamic Acid SCHEMBL27370161 0.76 IRAK4 (0.61) PNLIPKMT2ATP53CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3606898-A1 COMPOSITIONS COMPRISING HYDROQUINONE AND CATECHOL, METHOD FOR PREPARING THESE COMPOSITIONS Rhodia Operations (FR) 2020-02-12 EP disclosed