Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | BAX | Q07812 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24926216 | 0.84 | ALDH1A1 (0.50) | LTA4HALDH1A1HTTMAPK1L3MBTL1 | |
| SCHEMBL4211500 | 0.84 | LTA4H (0.68) | LTA4HNR1H2BAXALDH1A1HTT | |
| SCHEMBL8591053 | 0.83 | HTR2A (0.56) | ALDH1A1HTTMAPK1L3MBTL1MEN1 | |
| SCHEMBL9483870 | 0.82 | LTA4H (0.73) | LTA4HNR1H2BAXALDH1A1HTT | |
| SCHEMBL2095173 | 0.81 | HSD17B1 (0.49) | ESR1ESR2NPSR1 | |
| SCHEMBL9658605 | 0.81 | CAMK2A (0.49) | LTA4HNR1H2BAXALDH1A1IRAK4 | |
| SCHEMBL21670387 | 0.80 | PNLIP (0.46) | LTA4HNR1H2BAXALDH1A1MEN1 | |
| SCHEMBL9588305 | 0.80 | LTA4H (0.77) | LTA4HNR1H2BAXALDH1A1HTT | |
| SCHEMBL28851801 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HTTMAPK1L3MBTL1MEN1 | |
| SCHEMBL6830292 | 0.79 | HTT (0.79) | LTA4HNR1H2BAXALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110943-A | Herbicides | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1992-05-05 | — | — | US | disclosed |
| US-5037759-A | Oxidation of substituted phenoxy propane by bacteria | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1991-08-06 | — | — | US | disclosed |
| EP-0319100-A2 | Process for the preparation of substituted phenoxy propanoic acids | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-06-07 | — | — | EP | disclosed |