SCHEMBL21670865

SCHEMBL21670865

CC(C)c1cccc(C(C)C)c1/N=C/c1cc(-c2ccccc2)n(C)n1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.33
DDB1 Q16531 2/20 0.33
CRBN Q96SW2 2/20 0.33
STAT3 P40763 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21670889 0.85 NPC1 (0.46) ALDH1A1NPC1RAB9A
SCHEMBL21670886 0.81 GAA (0.32) TSHR
SCHEMBL21670868 0.79 ALDH1A1 (0.33) ALDH1A1ALOX15TSHRNPC1RAB9A
SCHEMBL21670879 0.79 GRM5 (0.34) GRM5DDB1CRBNSTAT3ALDH1A1
SCHEMBL11988757 0.73 KMT2A (0.42) ALDH1A1ALOX15TSHRRAB9A
SCHEMBL21670371 0.72 KMT2A (0.32) ALOX15TSHR
SCHEMBL16386822 0.72 DDB1 (0.42) GRM5DDB1CRBNSTAT3ALDH1A1
SCHEMBL6906495 0.71 GABRA1 (0.38) TSHR
SCHEMBL3687037 0.71 GABRA1 (0.38) TSHR
SCHEMBL13284156 0.70 ALDH1A1 (0.38) ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708429-B2 Bidentate azolylamido metal-ligand complexes and olefin polymerization catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-25 US disclosed
US-11708429-B2 Bidentate azolylamido metal-ligand complexes and olefin polymerization catalysts DOW GLOBAL TECHNOLOGIES LLC (US) 2023-07-25 US disclosed
US-20210332165-A1 BIDENTATE AZOLYLAMIDO METAL-LIGAND COMPLEXES AND OLEFIN POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2021-10-28 US disclosed
WO-2020028240-A1 BIDENTATE AZOLYLAMIDO METAL-LIGAND COMPLEXES AND OLEFIN POLYMERIZATION CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708429-B2 Bidentate azolylamido metal-ligand complexes and olefin polymerization catalysts LIG4, PARG, PIN1 GRM5 2810/4885DDB1 695/4885CRBN 474/4885
US-20210332165-A1 BIDENTATE AZOLYLAMIDO METAL-LIGAND COMPLEXES AND OLEFIN POLYMERIZATION CATALYSTS LIG4, PARG, PIN1 GRM5 2810/4885DDB1 695/4885CRBN 474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.