Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21670865 | 0.79 | GRM5 (0.33) | GRM5NPC1RAB9ADDB1CRBN | |
| SCHEMBL14293370 | 0.71 | GRM5 (0.41) | GRM5MAPTNPSR1NPC1RAB9A | |
| SCHEMBL1780239 | 0.71 | DDB1 (0.43) | GRM5NPC1RAB9ADDB1CRBN | |
| SCHEMBL21670863 | 0.71 | ALDH1A1 (0.35) | MAPTHTTNPSR1NPC1RAB9A | |
| SCHEMBL6913232 | 0.70 | MAOA (0.47) | GRM5MAPTHTTNPSR1NPC1 | |
| SCHEMBL6913236 | 0.70 | MAOA (0.47) | GRM5MAPTHTTNPSR1NPC1 | |
| SCHEMBL5588352 | 0.70 | ALDH1A1 (0.38) | MAPTHTTNPSR1NPC1GAA | |
| SCHEMBL5588346 | 0.70 | ALDH1A1 (0.38) | MAPTHTTNPSR1NPC1GAA | |
| SCHEMBL13041054 | 0.69 | P2RY1 (0.34) | GRM5NPC1RAB9ADDB1CRBN | |
| SCHEMBL11048071 | 0.69 | ALDH1A1 (0.46) | MAPTHTTNPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708429-B2 | Bidentate azolylamido metal-ligand complexes and olefin polymerization catalysts | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708429-B2 | Bidentate azolylamido metal-ligand complexes and olefin polymerization catalysts | DOW GLOBAL TECHNOLOGIES LLC (US) | 2023-07-25 | — | — | US | disclosed |
| US-20210332165-A1 | BIDENTATE AZOLYLAMIDO METAL-LIGAND COMPLEXES AND OLEFIN POLYMERIZATION CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2021-10-28 | — | — | US | disclosed |
| WO-2020028240-A1 | BIDENTATE AZOLYLAMIDO METAL-LIGAND COMPLEXES AND OLEFIN POLYMERIZATION CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708429-B2 | Bidentate azolylamido metal-ligand complexes and olefin polymerization catalysts | LIG4, PARG, PIN1 | GRM5 2810/4885MAPT 410/4885HTT 2939/4885 |
| US-20210332165-A1 | BIDENTATE AZOLYLAMIDO METAL-LIGAND COMPLEXES AND OLEFIN POLYMERIZATION CATALYSTS | LIG4, PARG, PIN1 | GRM5 2810/4885MAPT 410/4885HTT 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.