Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 17/20 | 0.59 |
| ▸ | ACACA | Q13085 | 10/20 | 0.48 |
| ▸ | GRN | P28799 | 2/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547380 | 0.77 | ACACB (0.82) | ACACBACACA | |
| SCHEMBL2547814 | 0.77 | SLC6A2 (0.42) | — | |
| SCHEMBL28934593 | 0.76 | LMNA (0.50) | — | |
| SCHEMBL28934594 | 0.76 | LMNA (0.50) | — | |
| Trifluoroacetic Acid SCHEMBL1547790 | 0.76 | ACACB (0.60) | ACACBACACA | |
| SCHEMBL2551232 | 0.76 | ITGB3 (0.41) | — | |
| SCHEMBL2167761 | 0.74 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL1547288 | 0.74 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL1547851 | 0.74 | ACACB (1.00) | ACACBACACA | |
| SCHEMBL2167541 | 0.74 | PPARG (0.52) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183998-A1 | HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THE USE THEREOF | SANOFI-AVENTIS (FR) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110183998-A1 | HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THE USE THEREOF | CS, CYP11B1, GPR119 | ACACB 1290/4885ACACA 1283/4885GRN 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.