Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.55 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | GNPAT | O15228 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5239846 | 0.84 | NOD1 (0.56) | SLC6A5NOD1GNPATCA2 | |
| SCHEMBL13301142 | 0.84 | FOLH1 (0.52) | FOLH1NOD1 | |
| SCHEMBL13301145 | 0.81 | FOLH1 (0.56) | FOLH1NOD1GNPAT | |
| SCHEMBL11433243 | 0.79 | CPB2 (0.64) | FOLH1CPB2SLC6A5SLC15A2GNPAT | |
| SCHEMBL5215821 | 0.79 | FOLH1 (0.58) | FOLH1CPB2SLC6A5NOD1SLC15A2 | |
| SCHEMBL20477195 | 0.79 | FOLH1 (0.58) | FOLH1CPB2SLC6A5NOD1SLC15A2 | |
| SCHEMBL2494432 | 0.79 | SLC6A5 (0.59) | FOLH1CPB2SLC6A5NOD1SLC15A2 | |
| SCHEMBL19385942 | 0.79 | SLC6A5 (0.59) | FOLH1CPB2SLC6A5NOD1SLC15A2 | |
| SCHEMBL11708581 | 0.79 | FOLH1 (0.58) | FOLH1CPB2SLC6A5NOD1SLC15A2 | |
| SCHEMBL2494433 | 0.79 | SLC6A5 (0.59) | FOLH1CPB2SLC6A5NOD1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9045555-B2 | Vaccine against amyloid folding intermediate | DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) | 2015-06-02 | — | — | US | disclosed |
| EP-2297196-B1 | VACCINE AGAINST AMYLOID FOLDING INTERMEDIATE | NEDERLANDEN STAAT (NL) | 2012-11-14 | — | — | EP | disclosed |
| US-20110182928-A1 | VACCINE AGAINST AMYLOID FOLDING INTERMEDIATE | DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER VAN VWS (NL) | 2011-07-28 | — | — | US | disclosed |