Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.63 |
| ▸ | CTSL | P07711 | 7/20 | 0.63 |
| ▸ | CTSB | P07858 | 5/20 | 0.63 |
| ▸ | CTSK | P43235 | 5/20 | 0.63 |
| ▸ | TACR1 | P25103 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998432 | 0.89 | CTSL (0.64) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL7970776 | 0.88 | CTSL (0.65) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL18920606 | 0.88 | TACR1 (0.66) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL8234111 | 0.88 | TACR1 (0.66) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL8438830 | 0.88 | TACR1 (0.66) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL4154299 | 0.82 | TACR1 (0.67) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL12468262 | 0.80 | CTSL (0.52) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL8231722 | 0.80 | CTRB1 (0.61) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL8226672 | 0.79 | CTSB (0.55) | CTSSCTSLCTSBCTSKTACR1 | |
| SCHEMBL18930537 | 0.79 | CTSB (0.55) | CTSSCTSLCTSBCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |