Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.66 |
| ▸ | CTSL | P07711 | 4/20 | 0.65 |
| ▸ | CTSB | P07858 | 3/20 | 0.65 |
| ▸ | CTSS | P25774 | 3/20 | 0.65 |
| ▸ | CTSK | P43235 | 3/20 | 0.65 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.62 |
| ▸ | ITGAV | P06756 | 1/20 | 0.57 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234111 | 1.00 | TACR1 (0.66) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL18920606 | 1.00 | TACR1 (0.66) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7970776 | 0.90 | CTSL (0.65) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL5397012 | 0.89 | ITGB3 (0.64) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL21676550 | 0.88 | CTSS (0.63) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL479010 | 0.88 | TACR1 (0.68) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL220648 | 0.88 | TACR1 (0.68) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL219151 | 0.88 | TACR1 (0.68) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL7372270 | 0.88 | TACR1 (0.68) | TACR1CTSLCTSBCTSSCTSK | |
| SCHEMBL26661077 | 0.88 | TACR1 (0.68) | TACR1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |
| EP-0384362-B1 | Glycinderivatives | HOFFMANN LA ROCHE (CH) | 1999-12-15 | — | — | EP | disclosed |
| US-5663297-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0372486-B1 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | HOFFMANN LA ROCHE (CH) | 1994-06-01 | — | — | EP | disclosed |
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |
| EP-0372486-A2 | Benzoic-acid phenylacetic-acid derivatives, their preparation and their use as medicines | F. HOFFMANN-LA ROCHE AG (CH) | 1990-06-13 | — | — | EP | disclosed |