Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18920618 | 0.99 | MMP2 (0.44) | MMP2MMP3ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL21144742 | 0.99 | MMP2 (0.44) | MMP2MMP3ADRA1DADRA1AADRA1B | |
| SCHEMBL2370243 | 0.84 | EPHX1 (0.53) | CA12CA9TDP1ALDH1A1CASP3 | |
| SCHEMBL1529483 | 0.84 | EPHX1 (0.53) | CA12CA9TDP1ALDH1A1CASP3 | |
| SCHEMBL1529481 | 0.84 | EPHX1 (0.53) | CA12CA9TDP1ALDH1A1CASP3 | |
| Hydrochloric Acid SCHEMBL4778820 | 0.82 | EPHX1 (0.52) | CA12CA9TDP1ALDH1A1CASP3 | |
| Hydrochloric Acid SCHEMBL1529614 | 0.82 | EPHX1 (0.52) | CA12CA9TDP1ALDH1A1CASP3 | |
| Hydrochloric Acid SCHEMBL4783273 | 0.82 | EPHX1 (0.52) | CA12CA9TDP1ALDH1A1CASP3 | |
| Hydrochloric Acid SCHEMBL29574342 | 0.82 | EPHX1 (0.52) | CA12CA9TDP1ALDH1A1CASP3 | |
| SCHEMBL1529725 | 0.81 | CASP3 (0.57) | ADRA1DADRA1AADRA1BALDH1A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654818-B2 | Furane derivatives as inhibitors of ATAD2 | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-05-19 | — | — | US | disclosed |
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654818-B2 | Furane derivatives as inhibitors of ATAD2 | ATAD2, ATAD2B, TAF1L | MMP2 4044/4885MMP3 4298/4885ADRA1D 1546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.