Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 5/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168910 | 0.88 | SMN1; SMN2 (0.42) | ADRA1ALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2169831 | 0.87 | HPGD (0.40) | ADRA1ALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2171193 | 0.86 | HPGD (0.39) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2167682 | 0.85 | HPGD (0.38) | ADRA1ALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2168080 | 0.85 | POLB (0.36) | LMNANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL2169211 | 0.84 | ITK (0.38) | LMNAKDM4EALDH1A1POLBMAPT | |
| SCHEMBL2167567 | 0.84 | SMN1; SMN2 (0.36) | ADRA1ALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2169080 | 0.82 | MCHR1 (0.37) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2167566 | 0.82 | ADRA1A (0.37) | ADRA1ALMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2168083 | 0.82 | KDM5A (0.33) | LMNANPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |