SCHEMBL216778

SCHEMBL216778

C[C]1C(C)=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
IDO1 P14902 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
ALDH1A1 P00352 3/20 0.38
CDC25A P30304 2/20 0.38
CDC25B P30305 2/20 0.38
CYP3A4 P08684 2/20 0.38
MAPT P10636 2/20 0.38
PKM P14618 2/20 0.38
HPGD P15428 2/20 0.38
PLIN1 O60240 1/20 0.38
NR1I2 O75469 1/20 0.38
USP2 O75604 1/20 0.38
GSR P00390 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
GAA P10253 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270394 0.83
SCHEMBL28396284 0.77 CDC25A (0.37) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL678100 0.75 MAPT (0.61) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL19264047 0.75 DRD2 (0.43) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL8773107 0.73 CDC25B (0.57) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL4622300 0.73 LMNA (0.34) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL5078335 0.73 LMNA (0.35) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL30715504 0.73 CDC25B (0.57) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL4622261 0.73 CDC25A (0.34) LMNAIDO1MEN1KMT2AALDH1A1
SCHEMBL6351666 0.72 LMNA (0.33) LMNAIDO1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114716585-B Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2023-02-28 CN claimed
CN-113185545-B Benzylamino-containing side arm Shan Maodi quaternary metal complex and application thereof 吉林大学 2022-11-29 CN claimed
CN-114716585-A Catalyst system containing aryloxy side-arm metallocene fourth subgroup metal complex and application thereof 吉林大学 2022-07-08 CN claimed
CN-111729688-B Application of single cyclopentadienyl fourth subgroup metal complex containing neutral coordination side group 吉林大学 2021-08-17 CN claimed
CN-113185545-A Benzyl amino side arm-containing half-metallocene fourth subgroup metal complex and application thereof 吉林大学 2021-07-30 CN claimed
CN-111662338-B Monocyclopentadienyl fourth subgroup metal complex containing neutral amine or phosphine ligand side group and its use 吉林大学 2021-06-22 CN claimed
CN-108250340-B Metallocene catalyst system and method for catalyzing olefin polymerization by using same 北京引发科技有限公司 2021-03-19 CN claimed
CN-108250341-B Catalyst system containing metallocene compound and method for catalyzing olefin polymerization by using catalyst system 北京引发科技有限公司 2020-12-11 CN claimed
CN-111729688-A Application of single cyclopentadienyl fourth subgroup metal complex containing neutral coordination side group 吉林大学 2020-10-02 CN claimed
CN-111662338-A Monocyclopentadienyl fourth subgroup metal complex containing neutral amine or phosphine ligand side group and its use 吉林大学 2020-09-15 CN claimed
WO-2004076502-A1 SUPPORTED MULTINUCLEAR METALLOCENE CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PREPARING THE SAME HONAM PETROCHEMICAL CORPORATION (KR) 2004-09-10 WO claimed
US-20040072677-A1 Multinuclear metallocene catalyst HONAM PETROCHEMICAL CORPORATION (KR) 2004-04-15 US claimed
EP-1363955-A1 MULTINUCLEAR METALLOCENE CATALYST Honam Petrochemical Corporation (KR) 2003-11-26 EP claimed
US-20030092851-A1 Process for preparing partially hydrogenated butadiene polymers BANK OF AMERICA, N.A. 2003-05-15 US claimed
WO-2002060964-A1 MULTINUCLEAR METALLOCENE CATALYST HONAM PETROCHEMICAL CORPORATION (KR) 2002-08-08 WO claimed
US-6277934-B1 A SYNDIOTACTIC HOMO- OR COPOLYMER FROM A STYRENIC COMPOUND IN THE PRESENCE OF A METALLOCENE OF HIGH, STABLE ACTIVITY COMPRISING A TITANIUM COMPOUND AND AN ORGANIC ALUMINOXY COMPOUND OF SPECIFIC NUCLEAR MAGNETIC RESONANCE SPECTRUM IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-08-21 US claimed
EP-0948547-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION THEREOF Montell Technology Company bv (NL) 1999-10-13 EP claimed
EP-0918757-A1 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS GEORGETOWN UNIVERSITY (US) 1999-06-02 EP claimed
WO-1999021896-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION THEREOF MONTELL TECHNOLOGY COMPANY BV (NL) 1999-05-06 WO claimed
WO-1997043268-A1 8-HYDROCARBYL SUBSTITUTED BENZODIZOCINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PROTEIN KINASE C (=PKC) MODULATORS GEORGETOWN UNIVERSITY (US) 1997-11-20 WO claimed