SCHEMBL28396284

SCHEMBL28396284

C=[SiH2].CC1=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 2/20 0.37
CDC25B P30305 2/20 0.37
LMNA P02545 2/20 0.37
IDO1 P14902 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PLIN1 O60240 1/20 0.37
NR1I2 O75469 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GSR P00390 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
GAA P10253 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
HSPD1 P10809 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270394 0.92
SCHEMBL19264047 0.78 DRD2 (0.43) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL216778 0.77 LMNA (0.38) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL23569630 0.74 CDC25A (0.31) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL678100 0.73 MAPT (0.61) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL8773107 0.71 CDC25B (0.57) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL4622300 0.71 LMNA (0.34) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL5078335 0.71 LMNA (0.35) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL30715504 0.71 CDC25B (0.57) CDC25ACDC25BLMNAIDO1MEN1
SCHEMBL9471404 0.71 LMNA (0.50) LMNAMEN1KMT2AUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106866719-B Benzocyclobutene polycarbosilane polymerization monomer or resin and preparation method thereof 西南科技大学 2020-05-15 CN claimed
CN-106866719-B Benzocyclobutene polycarbosilane polymerization monomer or resin and preparation method thereof 西南科技大学 2020-05-15 CN disclosed
CN-106866719-A Benzocyclobutene Polycarbosilane polymerized monomer or resin and preparation method thereof 西南科技大学 2017-06-20 CN disclosed