Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21680819 | 0.98 | KMT2A (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL15415403 | 0.78 | HTT (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL30677857 | 0.76 | KMT2A (0.43) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21680885 | 0.76 | HTT (0.47) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL17273858 | 0.74 | KMT2A (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL4803949 | 0.74 | KMT2A (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL966438 | 0.74 | KMT2A (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3125309 | 0.72 | CHRM1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6238532 | 0.72 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL21138457 | 0.71 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1HTTCHRM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11147272-B2 | Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients | MITSUI CHEMICALS ARGRO, INC. (JP) | 2021-10-19 | — | — | US | disclosed |
| US-11000038-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-05-11 | — | — | US | disclosed |
| US-20200196600-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-06-25 | — | — | US | disclosed |
| EP-3611164-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |
| EP-3611166-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-20200045963-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200196600-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, PDXK, PLPBP | NPC1 4145/4885RAB9A 2877/4885SMN1; SMN2 3515/4885 |
| US-20200045963-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS | PNPO, PDXK, PLPBP | NPC1 4243/4885RAB9A 3434/4885SMN1; SMN2 2936/4885 |
| US-11147272-B2 | Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients | PNPO, PDXK, PLPBP | NPC1 4243/4885RAB9A 3434/4885SMN1; SMN2 2936/4885 |
| US-11000038-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, PDXK, PLPBP | NPC1 4145/4885RAB9A 2877/4885SMN1; SMN2 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.