Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 11/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8343878 | 0.88 | PPARA (0.55) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL2886858 | 0.87 | MAPT (0.80) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL4466321 | 0.86 | ALDH1A1 (0.56) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL8341727 | 0.85 | PPARA (0.62) | ALDH1A1NPC1GAAKDM4EPPARA | |
| SCHEMBL13407798 | 0.85 | ALDH1A1 (0.81) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL981341 | 0.85 | SMN1; SMN2 (0.71) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL4462657 | 0.85 | ALDH1A1 (0.71) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL12402761 | 0.84 | RAB9A (0.69) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL28297323 | 0.84 | MEN1 (0.64) | ALDH1A1NPC1GAAMEN1MAPT | |
| SCHEMBL3054846 | 0.83 | GAA (0.74) | ALDH1A1NPC1GAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-28 | — | — | US | disclosed |
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-28 | — | — | US | disclosed |
| US-7982050-B2 | Process for preparing ligands of PPARdelta and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-19 | — | — | US | disclosed |
| US-7982050-B2 | Process for preparing ligands of PPARdelta and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-19 | — | — | US | disclosed |
| US-7982050-B2 | Process for preparing ligands of PPARdelta and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2011-07-19 | — | — | US | disclosed |
| EP-1501811-B1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NAT UNIV IND FOUNDATION (KR) | 2009-07-15 | — | — | EP | disclosed |
| EP-1501811-B1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | SEOUL NAT UNIV IND FOUNDATION (KR) | 2009-07-15 | — | — | EP | disclosed |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | Kang, Heon Joong (KR) | 2009-05-07 | — | — | US | disclosed |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | Kang, Heon Joong (KR) | 2009-05-07 | — | — | US | disclosed |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | Kang, Heon Joong (KR) | 2009-05-07 | — | — | US | disclosed |
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-08-02 | — | — | US | disclosed |
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-08-02 | — | — | US | disclosed |
| US-7241901-B2 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-07-10 | — | — | US | disclosed |
| US-7241901-B2 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-07-10 | — | — | US | disclosed |
| US-7241901-B2 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2007-07-10 | — | — | US | disclosed |
| WO-2006121223-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | KANG HEON JOONG (KR) | 2006-11-16 | — | — | WO | disclosed |
| EP-1501811-A4 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | KANG HEONJOONG (KR) | 2006-02-08 | — | — | EP | disclosed |
| US-20050176785-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) | 2005-08-11 | — | — | US | disclosed |
| EP-1501811-A1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | Kang, Heonjoong (KR) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003106442-A1 | PROCESS FOR PREPARING THIAZOLE DERIVATIVE AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | KANG HEONJOONG (KR) | 2003-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179300-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | PPARD, PPARG, PPARA | ALDH1A1 816/4885NPC1 939/4885GAA 1661/4885 |
| US-20110184186-A1 | PROCESS FOR PREPARING LIGANDS OF PPARDELTA AND THE INTERMEDIATE COMPOUNDS FOR PREPARING THE SAME | PPARG, PPARD, PPARA | ALDH1A1 1346/4885NPC1 1035/4885GAA 1778/4885 |
| US-20090118516-A1 | Process for preparing ligands of ppardelta and the intermediate compounds for preparing the same | PPARG, PPARD, PPARA | ALDH1A1 1346/4885NPC1 1035/4885GAA 1778/4885 |
| US-20050176785-A1 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same | PPARD, PPARG, PPARA | ALDH1A1 816/4885NPC1 939/4885GAA 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.