SCHEMBL21684

SCHEMBL21684

Oc1ccccc1/C=C/c1cccc(O)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.61
ERN1 O75460 1/20 0.58
IAPP P10997 4/20 0.57
POLB P06746 2/20 0.56
GAA P10253 2/20 0.56
RAB9A P51151 1/20 0.56
RELA Q04206 1/20 0.55
NFKB1 P19838 2/20 0.54
CDK4 P11802 1/20 0.54
CCND1 P24385 1/20 0.54
JUN P05412 1/20 0.54
NFE2L2 Q16236 1/20 0.54
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA4 P22748 1/20 0.52
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL308223 0.93 ERN1 (0.65) TRPA1ERN1IAPPPOLBGAA
SCHEMBL717976 0.87 TRPA1 (0.76) TRPA1POLBRAB9ANFKB1CDK4
SCHEMBL108389 0.87 TRPA1 (0.76) TRPA1POLBRAB9ANFKB1CDK4
SCHEMBL717978 0.85 TRPA1 (0.73) TRPA1ERN1IAPPPOLBGAA
SCHEMBL9743428 0.85 TRPA1 (0.73) TRPA1ERN1IAPPPOLBGAA
SCHEMBL30279756 0.85 TRPA1 (0.73) TRPA1ERN1IAPPPOLBGAA
SCHEMBL3237524 0.84 ERN1 (0.56) TRPA1ERN1IAPPPOLBGAA
SCHEMBL18109190 0.81 TRPA1 (0.61) TRPA1NFKB1CDK4CCND1JUN
SCHEMBL9745412 0.79 IAPP (0.60) TRPA1ERN1IAPPPOLBGAA
SCHEMBL9251021 0.79 IAPP (0.60) TRPA1ERN1IAPPPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 390 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4436538-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION Merryvital AG (CH) 2024-10-02 EP claimed
EP-3859211-B1 HANDHELD LIGHTER WITH HIGH TEMPERATURE WARNING INDICATOR SOCIéTé BIC (FR) 2024-01-24 EP claimed
US-20230293458-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2023-09-21 US claimed
WO-2023094852-A1 COSMETIC OR PHARMACEUTICAL PREPARATION FOR SKIN CARE AND IMPROVING SKIN CONDITION MERRYVITAL AG (CH) 2023-06-01 WO claimed
EP-3634430-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME Flagship Pioneering Innovations V, Inc. (US) 2020-04-15 EP claimed
US-20200101030-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME KINTAI THERAPEUTICS, INC. 2020-04-02 US claimed
CN-110869024-A Multi-biological agents and methods of use thereof 旗舰创业创新五公司 2020-03-06 CN claimed
US-20190308031-A1 SKIN DISORDER THERAPEUTICS AND METHODS OF USE SYMBIOME, INC. 2019-10-10 US claimed
WO-2018226732-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2018-12-13 WO claimed
US-20170087116-A1 Treatment of Inflammatory and Infectious Skin Disorders THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-03-30 US claimed
US-6521669-B1 Hydroxystilbene compounds for reducing/inhibiting protein glycation SOCIETE L'OREAL S.A. (FR) 2003-02-18 US claimed
US-6479466-B1 Compositions for treating viral infections, and methods therefor UNIVERSITY OF MARYLAND 2002-11-12 US claimed
EP-1234571-A1 Topical composition containing a hydroxystilbene and a polyol L'OREAL (FR) 2002-08-28 EP claimed
EP-1221949-A2 METHOD AND COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF SYMPTOMS ASSOCIATED WITH COLD AND INFLUENZA-LIKE ILLNESSES THE PROCTER & GAMBLE COMPANY (US) 2002-07-17 EP claimed
EP-1140097-A4 PRODUCTS COMPRISING TRIHYDROXYSTILBENES AND DERIVATIVES THEREOF AND METHODS FOR THEIR MANUFACTURE AND USE PURE WORLD BOTAN INC (US) 2002-05-08 EP claimed
US-6361815-B1 ISOLATION OF PURIFIED PRODUCT COMPRISING 85% BY WEIGHT OF 3,4',5-TRIHYDROXY-TRANS-STILBENE FROM PLANT MATERIAL CONTAINING TRIHYDROXYSTILBENES AND GLYCOSYLATED DERIVATIVES THEREOF PURE WORLD BOTANICALS, INC. 2002-03-26 US claimed
EP-1140097-A2 PRODUCTS COMPRISING TRIHYDROXYSTILBENES AND DERIVATIVES THEREOF AND METHODS FOR THEIR MANUFACTURE AND USE Pure World Botanicals, Inc. (US) 2001-10-10 EP claimed
WO-2001008671-A2 METHOD AND COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF SYMPTOMS ASSOCIATED WITH COLD AND INFLUENZA-LIKE ILLNESSES THE PROCTER & GAMBLE COMPANY (US) 2001-02-08 WO claimed
WO-2000037021-A2 PRODUCTS COMPRISING TRIHYDROXYSTILBENES AND DERIVATIVES THEREOF AND METHODS FOR THEIR MANUFACTURE AND USE PURE WORLD BOTANICALS, INC. (US) 2000-06-29 WO claimed
EP-0773020-A2 Pharmaceutical compositions containing L-carnitine or derivatives thereof in combination with resveratrol or derivatives thereof, for the prophylaxis and treatment of cardiovascular disorders, peripheral vascular diseases and peripheral diabetic neuropathy Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1997-05-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200101030-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME SI, FABP2, CEL TRPA1 4291/4885ERN1 3636/4885IAPP 65/4885
US-20230293458-A1 MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME SI, FABP2, CEL TRPA1 4291/4885ERN1 3636/4885IAPP 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.