Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21686490 | 0.86 | KCNH2 (0.39) | PDK1KCNH2NR1H2NR1H3BRD4 | |
| SCHEMBL21686442 | 0.84 | PDK1 (0.42) | PDK1KCNH2NR1H2NR1H3CHRNA7 | |
| SCHEMBL21686491 | 0.84 | EGFR (0.51) | KCNH2NR1H2NR1H3L3MBTL1RIOK2 | |
| SCHEMBL21686643 | 0.81 | PDK1 (0.38) | PDK1KCNH2BRD4CHRNA7L3MBTL1 | |
| SCHEMBL24279192 | 0.81 | PDK1 (0.40) | PDK1KCNH2CHRNA7MAPTSMN1; SMN2 | |
| SCHEMBL24282174 | 0.77 | CHRNA7 (0.44) | PDK1CHRNA7TSHRCYP2C19HIF1A | |
| SCHEMBL21686606 | 0.76 | GLO1 (0.42) | KCNH2NR1H2NR1H3L3MBTL1MAOA | |
| SCHEMBL21686488 | 0.73 | MAPT (0.56) | KCNH2NR1H2NR1H3CASP3SENP7 | |
| SCHEMBL21686464 | 0.73 | MAPT (0.49) | KCNH2NR1H2NR1H3CASP3SENP7 | |
| SCHEMBL24358410 | 0.72 | PHLPP2 (0.58) | KCNH2NR1H2NR1H3L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3362518-B1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | THE UWM RES FOUNDATION INC (US) | 2022-04-27 | — | — | EP | disclosed |
| US-11275071-B2 | Sensor dyes for real-time sensing of metal ions in aqueous environments | UWM RESEARCH FOUNDATION, INC. (US) | 2022-03-15 | — | — | US | disclosed |
| US-20200033314-A1 | SENSOR DYES FOR REAL-TIME SENSING OF METAL IONS IN AQUEOUS ENVIRONMENTS | ADVANCED CHEMICAL SYSTEMS, INC. | 2020-01-30 | — | — | US | disclosed |