SCHEMBL2168943

SCHEMBL2168943

CC1CC(C)C(=O)OC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GMNN O75496 1/20 0.36
PPM1B O75688 1/20 0.36
LMNA P02545 1/20 0.36
PPP1CC P36873 1/20 0.36
TFPI2 P48307 1/20 0.36
RAB9A P51151 1/20 0.36
PPP5C P53041 1/20 0.36
PPP1CA P62136 1/20 0.36
PMP22 Q01453 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36
CA1 P00915 2/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7310733 1.00 SMN1; SMN2 (0.36) SMN1; SMN2KDM4EGMNNPPM1BLMNA
SCHEMBL1330580 1.00 SMN1; SMN2 (0.36) SMN1; SMN2KDM4EGMNNPPM1BLMNA
SCHEMBL16003245 0.82 KDM4E (0.30) SMN1; SMN2KDM4EGMNNPPM1BLMNA
SCHEMBL18789034 0.78 POLB (0.36)
SCHEMBL16657577 0.76
SCHEMBL18588303 0.76
SCHEMBL2692834 0.76
SCHEMBL7085873 0.71 CA1 (0.32) SMN1; SMN2CA1CA2CA4KMT2A
SCHEMBL18427530 0.71 SMN1; SMN2 (0.44) SMN1; SMN2KDM4EGMNNPPM1BLMNA
SCHEMBL7282746 0.71 SMN1; SMN2 (0.33) SMN1; SMN2KDM4EGMNNPPM1BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024175529-A1 HOT-MELT COMPOSITION BOSTIK SA (FR) 2024-08-29 WO claimed
EP-4594382-A1 OPTIONALLY SILYLATED IONIC POLYURETHANE(S) Bostik SA (FR) 2025-08-06 EP disclosed
CN-120041103-A Active energy ray-curable adhesive and laminate 爱天思株式会社 2025-05-27 CN disclosed
EP-4527993-A1 METHOD OF MANUFACTURING BIODEGRADABLE NONWOVEN FABRIC AND BIODEGRADABLE NONWOVEN FABRIC MANUFACTURED THEREBY SK leaveo Co., Ltd. (KR) 2025-03-26 EP disclosed
US-20250075384-A1 METHOD OF MANUFACTURING BIODEGRADABLE NONWOVEN FABRIC AND BIODEGRADABLE NONWOVEN FABRIC MANUFACTURED THEREBY SK LEAVEO CO., LTD. (KR) 2025-03-06 US disclosed
WO-2025009755-A1 BIODEGRADABLE BUOY AND MANUFACTURING METHOD THEREOF 에스케이리비오 주식회사 2025-01-09 WO disclosed
WO-2024262832-A1 BIODEGRADABLE FILM, MANUFACTURING METHOD THEREFOR, AND BIODEGRADABLE RESIN COMPOSITION 에스케이리비오 주식회사 2024-12-26 WO disclosed
US-12098242-B2 Biodegradable polyester resin composition, biodegradable polyester film including the same and biodegradable molded article including biodegradable polyester resin composition ECOVANCE CO. LTD. (KR) 2024-09-24 US disclosed
WO-2024175529-A1 HOT-MELT COMPOSITION BOSTIK SA (FR) 2024-08-29 WO disclosed
US-11999847-B2 Biodegradable molded article and biodegradable polyester resin composition ECOVANCE CO. LTD. (KR) 2024-06-04 US disclosed
WO-2004110609-A2 CATALYTIC ASYMMETRIC DESYMMETRIZATION OF PROCHIRAL AND MESO CYCLIC ANHYDRIDES BRANDEIS UNIVERSITY (US) 2004-12-23 WO disclosed
US-20040082809-A1 Catalytic asymmetric desymmetrization of prochiral and meso compounds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-04-29 US disclosed
US-20030171610-A1 Catalyst asymmetric desymmetrization of prochiral compounds DENG LI (US) 2003-09-11 US disclosed
US-6580003-B2 Reacting a prochiral compound comprising two chiral centers, and internal plane of symmetry or point of symmetry or both, with a nucleophile in presence of a chiral, non-racemic tertiary amine catalyst, thereby producing a chiral compound BRANDEIS UNIVERSITY 2003-06-17 US disclosed
EP-1268368-A2 CATALYTIC ASYMMETRIC DESYMMETRIZATION OF MESO COMPOUNDS Brandeis University (US) 2003-01-02 EP disclosed
US-20020038048-A1 Catalytic asymmetric desymmetrization of meso compounds BRANDEIS UNIVERSITY 2002-03-28 US disclosed
WO-2001074741-A2 CATALYTIC ASYMMETRIC DESYMMETRIZATION OF MESO COMPOUNDS BRANDEIS UNIVERSITY (US) 2001-10-11 WO disclosed
EP-0505481-A1 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES RHONE-POULENC SANTE (FR) 1992-09-30 EP disclosed
WO-1991009030-A1 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES RHONE-POULENC SANTE (FR) 1991-06-27 WO disclosed
US-4996158-A Optical resolution of racemic alcohols LION CORPORATION, 3-7, HONJO 1-CHOME, SUMIDA-KU, TOKYO, JAPAN 1991-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020038048-A1 Catalytic asymmetric desymmetrization of meso compounds DNPH1, HDHD5, GNE SMN1; SMN2 3998/4885KDM4E 2135/4885GMNN 402/4885
US-20030171610-A1 Catalyst asymmetric desymmetrization of prochiral compounds HPSE, HPD, APEH SMN1; SMN2 4274/4885KDM4E 2505/4885GMNN 546/4885
US-20040082809-A1 Catalytic asymmetric desymmetrization of prochiral and meso compounds CA14, CA12, HPSE SMN1; SMN2 4193/4885KDM4E 2311/4885GMNN 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.