Thioglycolic Acid

Thioglycolic Acid

SCHEMBL216898

N.N.O=C(O)CS.O=C(O)CS

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
LDHA P00338 1/20 0.43
SRR Q9GZT4 1/20 0.43
ALKBH5 Q6P6C2 1/20 0.43
SUCNR1 Q9BXA5 1/20 0.43
EGLN1 Q9GZT9 1/20 0.43
FOLH1 Q04609 1/20 0.42
TSHR P16473 4/20 0.40
FFAR3 O14843 1/20 0.40
GLRA1 P23415 1/20 0.40
SLC6A9 P48067 1/20 0.40
OR51E2 Q9H255 1/20 0.40
ACE P12821 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.38
HSD17B10 Q99714 1/20 0.37
CYP2D6 P10635 3/20 0.35
CYP2C19 P33261 1/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL59070 1.00
Thioglycolic Acid SCHEMBL10397517 1.00 LMNA (0.43) LMNALDHASRRALKBH5SUCNR1
Thioglycolic Acid SCHEMBL5534035 1.00
Thioglycolic Acid SCHEMBL9439584 1.00 LMNA (0.43) LMNALDHASRRALKBH5SUCNR1
Thioglycolic Acid SCHEMBL7033331 1.00
Thioglycolic Acid SCHEMBL16796586 1.00 LMNA (0.43) LMNALDHASRRALKBH5SUCNR1
Thioglycolic Acid SCHEMBL6897361 0.96
Thioglycolic Acid SCHEMBL10805371 0.96
Thioglycolic Acid SCHEMBL8404154 0.96
Thioglycolic Acid SCHEMBL21581908 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4590782-A1 GAS-PHASE COMPOSITION FOR INHIBITING CORROSION EXPOSED TO CONDENSED WATER Arkema France (FR) 2025-07-30 EP claimed
EP-4441164-A1 FOAMING COMPOSITION COMPATIBLE WITH STEEL FOR THE ASSISTED RECOVERY OF HYDROCARBONS ARKEMA FRANCE (FR) 2024-10-09 EP claimed
EP-3939469-B1 HAIR HOLDER AND HAIR TREATMENT METHOD USING SAME KAO CORP (JP) 2024-09-11 EP claimed
WO-2024062191-A1 GAS-PHASE COMPOSITION FOR INHIBITING CORROSION EXPOSED TO CONDENSED WATER ARKEMA FRANCE (FR) 2024-03-28 WO claimed
WO-2023099848-A1 FOAMING COMPOSITION COMPATIBLE WITH STEEL FOR THE ASSISTED RECOVERY OF HYDROCARBONS ARKEMA FRANCE (FR) 2023-06-08 WO claimed
EP-3743270-B1 CAST-MOLDING PROCESS FOR PRODUCING UV-ABSORBING CONTACT LENSES ALCON INC (CH) 2022-06-08 EP claimed
US-20220119569-A1 Curable and Solvent Soluble Formulations and Methods of Making and Using Therof POLY6 TECHNOLOGIES, INC. 2022-04-21 US claimed
EP-3830318-A1 ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY COVENTYA S.p.A. (IT) 2021-06-09 EP claimed
US-20200062877-A1 Curable and Solvent Soluble Formulations and Methods of Making and Using Therof POLY6 TECHNOLOGIES, INC. 2020-02-27 US claimed
WO-2020025448-A1 ELECTROPLATING BATH FOR DEPOSITING A BLACK ALLOY, METHOD FOR THE ELECTROCHEMICAL DEPOSITION OF A BLACK ALLOY ON A SUBSTRATE, A BLACK ALLOY AND AN ARTICLE COATED WITH SUCH BLACK ALLOY COVENTYA S.P.A. (IT) 2020-02-06 WO claimed
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents L'OREAL S.A. (FR) 2006-06-01 US claimed
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant L'OREAL S.A. (FR) 2006-04-20 US claimed
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles L'OREAL S.A. (FR) 2006-04-20 US claimed
US-20060078522-A1 Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt L'OREAL S.A. (FR) 2006-04-13 US claimed
US-20020155081-A1 Use of tris(hydroxymethyl) aminomethane in cold permanent waving processes PROCTER & GAMBLE COMPANY, THE 2002-10-24 US claimed
US-5520909-A WATER SOLUBLE DISULFIDES AND MERCAPTAN REDUCING AGENTS FOR RELAXING HAIR CONAIR CORPORATION (US) 1996-05-28 US claimed
EP-0443741-B1 Formulating device for cosmetically functional cosmetic products REVLON CONSUMER PROD CORP (US) 1995-06-14 EP claimed
US-4913900-A AQUEOUS SOLUTION OF THIOGLYCOLATE AND DITHIODIGLYCOLATE SALTS, POLYHYDRIC MOISTURIZER, ALKALI; SUITABLE FOR DAMAGED HAIR HELENE CURTIS, INC. (US) 1990-04-03 US claimed
EP-0344653-A2 Conditioning perm wave composition and method Helene Curtis Industries, Inc. (US) 1989-12-06 EP claimed
US-4572220-A Composition for altering the configuration of hair HELENE CURTIS INDUSTRIES, INC. (US) 1986-02-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020155081-A1 Use of tris(hydroxymethyl) aminomethane in cold permanent waving processes MGMT, TET1, TET3 LMNA 2446/4885LDHA 1946/4885SRR 1010/4885
US-20060083762-A1 Uses of compositions comprising electrophilic monomers and micro-particles or nanoparticles KRT18, PRKDC, ACP1 LMNA 916/4885LDHA 1702/4885SRR 4826/4885
US-20060115445-A1 Compositions for treating keratin materials comprising electrophilic monomers and liquid crystal agents KRT18, PRKDC, CUTA LMNA 953/4885LDHA 2636/4885SRR 3891/4885
US-20060083706-A1 Haircare composition comprising at least one electrophilic monomer and micro- or nanoparticles of at least one solid lubricant MITF, CUTA, NACA LMNA 2622/4885LDHA 755/4885SRR 2519/4885
US-20060078522-A1 Composition for treating keratin materials comprising at least one electrophilic monomer and at least one salt KRT18, DSG1, DSC1 LMNA 1665/4885LDHA 3988/4885SRR 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.