Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RELA | Q04206 | 4/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21690865 | 0.98 | POLB (0.32) | RELAHRH4HRH3POLBRAB9A | |
| SCHEMBL21690862 | 0.92 | — | — | |
| SCHEMBL21691005 | 0.79 | GRIA1 (0.34) | RELAHRH4HRH3 | |
| SCHEMBL22800827 | 0.79 | EPHX2 (0.41) | HRH4HRH3POLBRAB9A | |
| SCHEMBL25751747 | 0.78 | RELA (0.41) | RELA | |
| SCHEMBL21690942 | 0.78 | — | — | |
| SCHEMBL21690627 | 0.78 | — | — | |
| SCHEMBL7101767 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL353687 | 0.77 | APP (0.41) | HRH4HRH3POLBRAB9A | |
| SCHEMBL2197372 | 0.77 | FAAH (0.43) | RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247984-B2 | Uracil containing compounds | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2022-02-15 | — | — | US | disclosed |
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039966-A1 | URACIL CONTAINING COMPOUNDS | UNG, DPYD, DUT | RELA 3020/4885HRH4 4564/4885HRH3 4212/4885 |
| US-11247984-B2 | Uracil containing compounds | UNG, DPYD, DUT | RELA 3020/4885HRH4 4564/4885HRH3 4212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.