Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092470 | 0.91 | ACHE (0.40) | GPBAR1ACHEPRSS1CNR1CNR2 | |
| SCHEMBL20958110 | 0.86 | PLA2G2A (0.53) | CNR1CNR2 | |
| SCHEMBL20644678 | 0.83 | PRSS1 (0.35) | PRSS1PRSS2PRSS3PTPRCPTPRF | |
| SCHEMBL6873901 | 0.82 | TP53 (0.38) | GPBAR1ACHEPRSS1CNR1CNR2 | |
| SCHEMBL13685959 | 0.82 | PLA2G2A (0.36) | GPBAR1ACHEPRSS1CNR1CNR2 | |
| SCHEMBL24142770 | 0.82 | ITGB3 (0.41) | GPBAR1F2 | |
| SCHEMBL17407555 | 0.82 | PLA2G2A (0.51) | TSHRCNR1CNR2TP53 | |
| SCHEMBL16281533 | 0.80 | ALDH1A1 (0.48) | GPBAR1ACHESMN1; SMN2TSHRCYP4F2 | |
| SCHEMBL5486708 | 0.80 | PLA2G2A (0.54) | TSHRCNR1CNR2TP53 | |
| SCHEMBL2712563 | 0.80 | PLA2G2A (0.54) | TSHRCNR1CNR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200040141-A1 | ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-02-06 | — | — | US | disclosed |