Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21693313 | 0.88 | MAOA (0.41) | HPGDMAOAMAOBADRA1ADRD2 | |
| SCHEMBL17952763 | 0.86 | ADRA1A (0.39) | HPGDADRA1ADRD2DRD4HTR2A | |
| SCHEMBL21693365 | 0.86 | HPGD (0.40) | HPGDMAOAMAOBADRA1ADRD2 | |
| SCHEMBL21693175 | 0.78 | HPGD (0.41) | HPGDMAOAMAOBEEDADRA2A | |
| SCHEMBL17952917 | 0.78 | HPGD (0.41) | HPGDMAOAMAOBALDH1A1EED | |
| SCHEMBL12674655 | 0.78 | HPGD (0.34) | HPGDADRA1ADRD2DRD4HTR2A | |
| SCHEMBL17952751 | 0.76 | MAOA (0.37) | MAOAMAOBALDH1A1TNF | |
| SCHEMBL21693048 | 0.76 | ALDH1A1 (0.42) | MAOAMAOBALDH1A1ADRA2AADRA2B | |
| SCHEMBL1102505 | 0.76 | HPGD (0.38) | HPGDMAOAMAOBADRA1ADRD2 | |
| SCHEMBL12674654 | 0.76 | DRD2 (0.33) | HPGDADRA1ADRD2DRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |