SCHEMBL814607

SCHEMBL814607

C[SiH](C)[Hf](C)(C)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.33
HTR6 P50406 1/20 0.33
SIGMAR1 Q99720 4/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630556 0.81 HTR2A (0.34) HTR2AHTR6SIGMAR1KDM4ELMNA
SCHEMBL7634063 0.81 SIGMAR1 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL1130441 0.80 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL216950 0.80 HTR6 (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL7629863 0.77 SIGMAR1 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL3384862 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL3380486 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8206241 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL3383168 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL3382549 0.77 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3487924-B1 ROTOMOLDED COMPOSITIONS, ARTICLES, AND PROCESSES FOR MAKING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-06-12 EP claimed
WO-2021194831-A1 ALKYLATION OF TRANSITION METAL COORDINATION CATALYST COMPLEXES EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-09-30 WO claimed
US-10995203-B2 Rotomolded compositions, articles, and processes for making the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-05-04 US claimed
EP-3784677-A1 NON-COORDINATING ANION TYPE ACTIVATORS CONTAINING CATION HAVING LARGE ALKYL GROUPS ExxonMobil Chemical Patents Inc. (US) 2021-03-03 EP claimed
US-10676547-B2 Aluminum alkyls with pendant olefins on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-09 US claimed
US-20190284376-A1 Rotomolded Compositions, Articles, and Processes for Making the Same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-19 US claimed
EP-3487924-A1 ROTOMOLDED COMPOSITIONS, ARTICLES, AND PROCESSES FOR MAKING THE SAME ExxonMobil Chemical Patents Inc. (US) 2019-05-29 EP claimed
US-20180201700-A1 Aluminum Alkyls with Pendant Olefins on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2018-07-19 US claimed
EP-3344385-A1 ALUMINUM ALKYLS WITH PENDANT OLEFINS ON CLAYS ExxonMobil Chemical Patents Inc. (US) 2018-07-11 EP claimed
WO-2018017180-A1 ROTOMOLDED COMPOSITIONS, ARTICLES, AND PROCESSES FOR MAKING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-01-25 WO claimed
US-20110015357-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US claimed
US-7741417-B2 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
US-7385015-B2 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-10 US claimed
US-7220695-B2 Supported activator EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US claimed
US-20070055028-A1 Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEMICAL PATENTS INC. 2007-03-08 US claimed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
EP-0821703-A1 ETHYLENE-$g(a)-OLEFIN/DIOLEFIN POLYMER SOLUTION POLYMERIZATION PROCESS EXXON CHEMICAL PATENTS INC. (US) 1998-02-04 EP claimed
US-5696213-A HEATING IN PRESENCE OF A CATALYST SYSTEM EXXON CHEMICAL PATENTS INC. (US) 1997-12-09 US claimed
WO-1996033227-A1 ETHYLENE-α-OLEFIN/DIOLEFIN POLYMER SOLUTION POLYMERIZATION PROCESS EXXON CHEMICAL PATENTS INC. (US) 1996-10-24 WO claimed