Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GALK1 | P51570 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1131273 | 0.97 | KDM4E (0.33) | KDM4EENPP3ENPP1ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL219395 | 0.87 | KDM4E (0.31) | KDM4EENPP3ENPP1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL217589 | 0.85 | KDM4E (0.32) | KDM4EALDH1A1CYP2A6MAPTNPC1 | |
| Hydrochloric Acid SCHEMBL2114856 | 0.83 | DHFR (0.36) | KDM4EENPP3ENPP1ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL3673543 | 0.83 | NPC1 (0.35) | MAPTNPC1RAB9ASMN1; SMN2MTNR1A | |
| Hydrochloric Acid SCHEMBL7926942 | 0.82 | KDM4E (0.34) | KDM4EENPP3ENPP1ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL3759506 | 0.81 | KDM4E (0.33) | KDM4EENPP3ENPP1ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7211659 | 0.81 | KDM4E (0.33) | KDM4EENPP3ENPP1ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL339001 | 0.81 | KDM4E (0.33) | KDM4EENPP3ENPP1ALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7724262 | 0.81 | KDM4E (0.33) | KDM4EENPP3ENPP1ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065784-A1 | NOVEL ALUMINUM ALKYL WITH C5 CYCLIC AND PENDENT OLEFIN POLYMERIZATION CATALYST | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-05-07 | — | — | WO | claimed |
| US-20150119540-A1 | Novel Aluminum Alkyl With C5 Cyclic and Pendent Olefin Polymerization Catalyst | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-04-30 | — | — | US | claimed |
| US-8426534-B2 | Impact copolymer in single reactor | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2013-04-23 | — | — | US | claimed |
| EP-1799726-B1 | TRIALKYLALUMINUM TREATED SUPPORTS | EXXONMOBIL CHEM PATENTS INC (US) | 2011-07-13 | — | — | EP | claimed |
| US-7807769-B2 | Isotactic polypropylene produced from supercritical polymerization process | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-10-05 | — | — | US | claimed |
| EP-2231726-A1 | ISOTACTIC POLYPROPYLENE PRODUCED FROM SUPERCRITICAL POLYMERIZATION PROCESS | ExxonMobil Chemical Patents Inc. (US) | 2010-09-29 | — | — | EP | claimed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| WO-2009123663-A1 | ISOTACTIC POLYPROPYLENE PRODUCED FROM SUPERCRITICAL POLYMERIZATION PROCESS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-10-08 | — | — | WO | claimed |
| US-20090118447-A1 | Impact Copolymer in Single Reactor | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2009-05-07 | — | — | US | claimed |
| US-20080214767-A1 | Isotactic Polypropylene Produced From Supercritical Polymerization Process | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-09-04 | — | — | US | claimed |
| US-7385015-B2 | Trialkylaluminum treated supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-06-10 | — | — | US | claimed |
| EP-1922343-A2 | IMPACT COPOLYMER OF PROPYLENE PREPARED IN SINGLE REACTOR | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2008-05-21 | — | — | EP | claimed |
| WO-2007107189-A2 | IMPACT COPOLYMER OF PROPYLENE PREPARED IN SINGLE REACTOR | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2007-09-27 | — | — | WO | claimed |
| EP-1799726-A1 | TRIALKYLALUMINUM TREATED SUPPORTS | Exxonmobil Chemical Patents Inc. (US) | 2007-06-27 | — | — | EP | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| WO-2006044058-A1 | TRIALKYLALUMINUM TREATED SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-10676547-B2 | Aluminum alkyls with pendant olefins on clays | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-06-09 | — | — | US | disclosed |
| US-10421921-B2 | Lubricants from mixed alpha-olefin feeds | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2019-09-24 | — | — | US | disclosed |
| US-6177376-B1 | REACTING METALLOCENE WITH ORGANOLITHIUM COMPOUND AND GRIGNARD COMPOUND, ACTIVATION, CONTACTING WITH SUPPORT | TARGOR GMBH (DE) | 2001-01-23 | — | — | US | disclosed |
| EP-0911349-A1 | Aromatic vinyl resin material and molded products thereof | Idemitsu Petrochemical Co., Ltd. (JP) | 1999-04-28 | — | — | EP | disclosed |