Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL216963 | 0.83 | KDM4E (0.33) | NPC1MAPTRAB9ASMN1; SMN2MTNR1A | |
| Hydrochloric Acid SCHEMBL7933167 | 0.82 | ALOX5 (0.34) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL7936151 | 0.82 | NPC1 (0.33) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Fluoride Ion SCHEMBL1131273 | 0.80 | KDM4E (0.33) | NPC1MAPTRAB9ASMN1; SMN2MTNR1A | |
| SCHEMBL3672744 | 0.75 | MAPT (0.36) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL3673546 | 0.75 | NPC1 (0.34) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL7933117 | 0.73 | ALOX5 (0.35) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL1044599 | 0.73 | HTR1A (0.32) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL7935514 | 0.72 | NPC1 (0.33) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL2114856 | 0.71 | DHFR (0.36) | NPC1MAPTRAB9ASMN1; SMN2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807769-B2 | Isotactic polypropylene produced from supercritical polymerization process | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-10-05 | — | — | US | claimed |
| EP-2231726-A1 | ISOTACTIC POLYPROPYLENE PRODUCED FROM SUPERCRITICAL POLYMERIZATION PROCESS | ExxonMobil Chemical Patents Inc. (US) | 2010-09-29 | — | — | EP | claimed |
| WO-2009123663-A1 | ISOTACTIC POLYPROPYLENE PRODUCED FROM SUPERCRITICAL POLYMERIZATION PROCESS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-10-08 | — | — | WO | claimed |
| US-20080214767-A1 | Isotactic Polypropylene Produced From Supercritical Polymerization Process | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-09-04 | — | — | US | claimed |
| US-7807769-B2 | Isotactic polypropylene produced from supercritical polymerization process | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-10-05 | — | — | US | disclosed |
| EP-2231726-A1 | ISOTACTIC POLYPROPYLENE PRODUCED FROM SUPERCRITICAL POLYMERIZATION PROCESS | ExxonMobil Chemical Patents Inc. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009123663-A1 | ISOTACTIC POLYPROPYLENE PRODUCED FROM SUPERCRITICAL POLYMERIZATION PROCESS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-10-08 | — | — | WO | disclosed |
| US-20080214767-A1 | Isotactic Polypropylene Produced From Supercritical Polymerization Process | EXXONMOBIL CHEMICAL PATENTS INC. | 2008-09-04 | — | — | US | disclosed |