Hydrochloric Acid

Hydrochloric Acid

SCHEMBL217589

CC1=C(c2cccc3ccccc23)c2ccccc2C1[Zr+2](C1C(C)=C(c2cccc3ccccc23)c2ccccc21)[SiH](c1ccccc1)c1ccccc1.[Cl-].[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 1/20 0.31
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CYP2A6 P11509 1/20 0.30
DHFR P00374 1/20 0.30
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL219395 0.89 KDM4E (0.31) KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL216963 0.85 KDM4E (0.33) KDM4EALDH1A1HPGDNPC1MAPT
Fluoride Ion SCHEMBL1131273 0.83 KDM4E (0.33) KDM4EALDH1A1HPGDNPC1MAPT
Hydrochloric Acid SCHEMBL2114856 0.80 DHFR (0.36) KDM4EALDH1A1HPGDNPC1MAPT
Hydrochloric Acid SCHEMBL7926942 0.79 KDM4E (0.34) KDM4EALDH1A1HPGDMAPTCYP2A6
Hydrochloric Acid SCHEMBL3735013 0.78 KDM4E (0.32) KDM4EALDH1A1HPGDMAPTCYP2A6
Hydrochloric Acid SCHEMBL3759506 0.77 KDM4E (0.33) KDM4EALDH1A1HPGDMAPTCYP2A6
Hydrochloric Acid SCHEMBL7211659 0.77 KDM4E (0.33) KDM4EALDH1A1HPGDNPC1MAPT
Hydrochloric Acid SCHEMBL339001 0.77 KDM4E (0.33) KDM4EALDH1A1HPGDMAPTCYP2A6
Hydrochloric Acid SCHEMBL7724262 0.77 KDM4E (0.33) KDM4EALDH1A1HPGDMAPTCYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
US-8748361-B2 Polyalpha-olefin compositions and processes to produce the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-06-10 US disclosed
US-20140066567-A1 Multiple Catalyst System for Olefin Polymerization and Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2014-03-06 US disclosed
US-20070117941-A1 Syndiotactic propylene elastomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-05-24 US disclosed
EP-1753796-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2007-02-21 EP disclosed
WO-2007011832-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed
WO-2007011462-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed
WO-2007011459-A1 POLYALPHA-OLEFIN COMPOSITIONS AND PROCESSES TO PRODUCE THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed
WO-2005113622-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-12-01 WO disclosed
EP-1558655-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2005-08-03 EP disclosed
US-20040220359-A1 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-04 US disclosed
US-20040138392-A1 polyolefin adhesives; to produce reactor blends (also called intimate blends) of various polymers and other polymer compositions. EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-15 US disclosed
WO-2004046214-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 KDM4E 3458/4885ALDH1A1 3012/4885HPGD 4100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.