Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.60 |
| ▸ | PREP | P48147 | 2/20 | 0.54 |
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23502313 | 0.89 | FKBP1A (0.62) | FKBP1APREPACELMNASMN1; SMN2 | |
| SCHEMBL7333471 | 0.87 | FKBP1A (0.60) | FKBP1APREPACELMNASMN1; SMN2 | |
| SCHEMBL11940447 | 0.86 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL6788139 | 0.86 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL6788131 | 0.86 | FKBP1A (0.64) | FKBP1APREPACE | |
| SCHEMBL8053379 | 0.84 | FKBP1A (0.57) | FKBP1APREPACELMNA | |
| SCHEMBL18806512 | 0.84 | FKBP1A (0.61) | FKBP1APREPACE | |
| SCHEMBL10343310 | 0.84 | FKBP1A (0.61) | FKBP1APREPACE | |
| SCHEMBL6789001 | 0.83 | FKBP1A (0.58) | FKBP1APREPACE | |
| SCHEMBL6789016 | 0.83 | FKBP1A (0.58) | FKBP1APREPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |