Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 9/20 | 0.44 |
| ▸ | FAP | Q12884 | 8/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 8/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.35 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13437289 | 0.83 | FAP (0.44) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL29457960 | 0.81 | REN (0.58) | REN | |
| SCHEMBL10704033 | 0.81 | REN (0.45) | PREPFAPREN | |
| SCHEMBL10604758 | 0.78 | KMT2A (0.43) | PREPFAP | |
| SCHEMBL10604749 | 0.78 | KMT2A (0.43) | PREPFAP | |
| SCHEMBL10605519 | 0.78 | KMT2A (0.43) | PREPFAP | |
| SCHEMBL9284477 | 0.78 | PREP (0.40) | PREPFAPRENDPP8DPP9 | |
| SCHEMBL16670795 | 0.77 | DPP4 (0.57) | PREPFAPDPP8DPP9DPP4 | |
| SCHEMBL12001763 | 0.77 | ACE (0.41) | PREPFAPRENDPP8DPP9 | |
| SCHEMBL10656223 | 0.76 | REN (0.53) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |