SCHEMBL2169741

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2183002	0.90	CYP3A4 (0.49)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL2170217	0.90	SMN1; SMN2 (0.49)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL2169945	0.89	HTR6 (0.50)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL2183994	0.89	CYP3A4 (0.49)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL2169936	0.88	HTR6 (0.49)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL6117477	0.88	TP53 (0.47)	CYP3A4HTR6SMN1; SMN2TP53PKM
	Hydrochloric Acid SCHEMBL6118475	0.88	CYP3A4 (0.48)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL2169701	0.86	HTR6 (0.47)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL2170321	0.85	CYP3A4 (0.59)	CYP3A4CYP2D6HTR6DRD2HTR2A
	SCHEMBL2170110	0.82	L3MBTL1 (0.52)	CYP3A4HTR6HTR2AHTR2CDRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.