Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.43 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.43 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28128705 | 0.80 | PARP10 (0.67) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL11700754 | 0.78 | PARP10 (0.61) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL21697489 | 0.78 | PARP10 (0.45) | PARP10MAOBCHEK2SLC6A2SLC6A4 | |
| SCHEMBL30289581 | 0.77 | PARP10 (0.67) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL1029516 | 0.76 | CAMK2A (0.50) | TTR | |
| SCHEMBL8059639 | 0.76 | TTR (0.62) | TTRSCN9ARXRARXRBRXRG | |
| SCHEMBL11702647 | 0.75 | PARP10 (0.61) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL21697483 | 0.75 | PARP10 (0.56) | PARP10PARP15PARP14TNKSTNKS2 | |
| SCHEMBL8923163 | 0.75 | RXRA (0.47) | PARP10PARP15TTRRXRARXRB | |
| SCHEMBL21244290 | 0.74 | SCN8A (0.57) | PARP10CTNNB1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607944-A1 | NOVEL CYCLIN-DEPENDENT KINASE 8 AND/OR 19 INHIBITOR | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2020-02-12 | — | — | EP | disclosed |