Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711933 | 0.83 | TGM2 (0.58) | PKMSMN1; SMN2POLB | |
| SCHEMBL6744907 | 0.77 | KMT2A (0.70) | KMT2APKMALDH1A1GAAMEN1 | |
| SCHEMBL6744239 | 0.75 | ALDH1A1 (0.71) | KMT2APKMALDH1A1GAALMNA | |
| SCHEMBL1870003 | 0.74 | PKM (0.55) | KMT2APKMALDH1A1GAAMEN1 | |
| SCHEMBL4003507 | 0.74 | ALDH1A1 (0.53) | KMT2APKMALDH1A1GAAMEN1 | |
| SCHEMBL20502397 | 0.74 | ALDH1A1 (0.54) | KMT2APKMALDH1A1GAAMEN1 | |
| SCHEMBL5443874 | 0.74 | GPR183 (0.63) | KMT2APKMALDH1A1LMNA | |
| SCHEMBL5915285 | 0.74 | LMNA (0.70) | KMT2APKMSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19858517 | 0.73 | PKM (0.76) | PKMSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL22558460 | 0.73 | LMNA (0.43) | SMN1; SMN2ALDH1A1LMNAL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346807-A1 | NAPHTHYLACETIC ACIDS | F. Hoffmann-La Roche AG (CH) | 2011-07-27 | — | — | EP | disclosed |
| WO-2010055005-A1 | NAPHTHYLACETIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-05-20 | — | — | WO | disclosed |