Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 7/20 | 0.36 |
| ▸ | THRB | P10828 | 7/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2762233 | 0.91 | THRA (0.39) | LMNAMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL16496563 | 0.84 | THRB (0.38) | LMNAMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL2169679 | 0.84 | THRB (0.38) | LMNAMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL2169971 | 0.84 | THRA (0.44) | LMNAMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL2170345 | 0.80 | THRA (0.44) | THRATHRB | |
| SCHEMBL2170341 | 0.80 | THRA (0.44) | THRATHRB | |
| SCHEMBL2170699 | 0.79 | TNFRSF1A (0.40) | LMNAMEN1MAPTKMT2APOLB | |
| SCHEMBL2170701 | 0.79 | TNFRSF1A (0.40) | LMNAMEN1MAPTKMT2APOLB | |
| SCHEMBL2169568 | 0.79 | THRB (0.37) | LMNAKMT2ATHRATHRB | |
| SCHEMBL16496483 | 0.79 | THRB (0.37) | LMNAKMT2ATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346814-A2 | THYROID RECEPTOR LIGANDS | Cadila Healthcare Limited (IN) | 2011-07-27 | — | — | EP | disclosed |