Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 12/20 | 0.39 |
| ▸ | THRB | P10828 | 12/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2169968 | 0.91 | LMNA (0.40) | THRATHRBMEN1LMNAMAPT | |
| SCHEMBL2170341 | 0.87 | THRA (0.44) | THRATHRB | |
| SCHEMBL2170345 | 0.87 | THRA (0.44) | THRATHRB | |
| SCHEMBL2169361 | 0.83 | THRB (0.41) | THRATHRB | |
| SCHEMBL16496562 | 0.83 | THRB (0.41) | THRATHRB | |
| SCHEMBL2170237 | 0.83 | THRA (0.47) | THRATHRB | |
| SCHEMBL2170241 | 0.83 | THRA (0.47) | THRATHRB | |
| SCHEMBL2169463 | 0.82 | THRA (0.45) | THRATHRB | |
| SCHEMBL2169479 | 0.80 | THRA (0.61) | THRATHRB | |
| SCHEMBL16496522 | 0.80 | THRA (0.61) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049946-A2 | THYROID RECEPTOR LIGANDS | CADILA HEALTHCARE LIMITED (IN) | 2010-05-06 | — | — | WO | disclosed |