Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.44 |
| ▸ | AOC2 | O75106 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2466699 | 0.89 | FFAR1 (0.55) | FFAR1SLC5A1SLC5A2AOC2MAOA | |
| SCHEMBL27988046 | 0.84 | MAOB (0.55) | FFAR1SLC5A1SLC5A2AOC2MAOA | |
| SCHEMBL10925185 | 0.82 | CA2 (0.52) | LMNAIDO1MEN1CYP1A2CYP2C9 | |
| SCHEMBL7011662 | 0.82 | FFAR1 (0.67) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| SCHEMBL4846241 | 0.81 | LMNA (0.54) | FFAR1SLC5A1SLC5A2AOC2MAOA | |
| SCHEMBL658360 | 0.80 | LMNA (0.54) | FFAR1SLC5A1SLC5A2AOC2MAOA | |
| SCHEMBL2170992 | 0.79 | FFAR1 (0.53) | FFAR1SLC5A1SLC5A2AOC2MAOA | |
| SCHEMBL1478337 | 0.78 | NAAA (0.51) | FFAR1SLC5A1SLC5A2TAAR1LMNA | |
| SCHEMBL15672830 | 0.78 | ALDH1A1 (0.48) | FFAR1SLC5A1SLC5A2AOC2MAOA | |
| SCHEMBL31577212 | 0.77 | NAAA (0.50) | FFAR1TAAR1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |