Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560913 | 0.81 | LMNA (0.66) | LMNAHTTRAB9AMAPTNPC1 | |
| SCHEMBL17560916 | 0.81 | LMNA (0.66) | LMNAHTTRAB9AMAPTNPC1 | |
| SCHEMBL19321533 | 0.71 | MAPT (0.64) | LMNAHTTRAB9AMAPTNPC1 | |
| SCHEMBL16224305 | 0.70 | SMN1; SMN2 (0.57) | LMNAHTTRAB9AMAPTNPC1 | |
| SCHEMBL17560933 | 0.70 | SMN1; SMN2 (0.57) | LMNAHTTRAB9AMAPTNPC1 | |
| SCHEMBL21626681 | 0.69 | RAB9A (0.73) | LMNAHTTRAB9AMAPTNPC1 | |
| SCHEMBL10112300 | 0.69 | MAPT (1.00) | LMNARAB9AMAPTNPC1CASP3 | |
| SCHEMBL31429960 | 0.69 | MAPT (1.00) | LMNARAB9AMAPTNPC1CASP3 | |
| SCHEMBL2020949 | 0.69 | RAB9A (0.71) | LMNAHTTRAB9AMAPTNPC1 | |
| SCHEMBL2020946 | 0.69 | RAB9A (0.71) | LMNAHTTRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562880-B2 | Methods for treating protozoan infections | NEOCULI PTY LTD. (AU) | 2020-02-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562880-B2 | Methods for treating protozoan infections | DPM1, ABCB11, PIGS | LMNA 2337/4885HTT 2244/4885RAB9A 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.