Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CDC42 | P60953 | 1/20 | 0.36 |
| ▸ | RAC1 | P63000 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21701145 | 0.81 | CYP3A4 (0.51) | ALDH1A1TSHRTUBB4ATUBBTUBA3C | |
| SCHEMBL23873713 | 0.81 | MAOB (0.38) | FFAR4ALDH1A1L3MBTL1TDP1PTGS2 | |
| SCHEMBL21701156 | 0.80 | MAOB (0.41) | ALDH1A1L3MBTL1TDP1TSHRMAPT | |
| SCHEMBL21701167 | 0.78 | TUBB4A (0.37) | ALDH1A1L3MBTL1TUBB4ATUBBTUBA3C | |
| SCHEMBL3233663 | 0.76 | RAPGEF4 (0.47) | ABCB1RAPGEF4GABRG2GABRB3GABRA3 | |
| SCHEMBL1194620 | 0.76 | RAPGEF4 (0.47) | ABCB1RAPGEF4GABRG2GABRB3GABRA3 | |
| SCHEMBL29034768 | 0.73 | MAPT (0.44) | ALDH1A1TDP1LMNAMAPT | |
| SCHEMBL27100252 | 0.72 | CYP3A4 (0.46) | ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL23873780 | 0.72 | MAOB (0.56) | TDP1PTGS2PTGS1CYP1A2MAPT | |
| SCHEMBL5498232 | 0.68 | RELA (0.66) | ABCB1ALDH1A1PTGS2PTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912704-B2 | Methods and compositions for substituted arylcycloheptane analogs | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20210300928-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2021-09-30 | — | — | US | disclosed |
| WO-2020033567-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2020-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300928-A1 | METHODS AND COMPOSITIONS FOR SUBSTITUTED ARYLCYCLOHEPTANE ANALOGS | AHR, HCCS, HMBS | ABCB1 195/4885RAPGEF4 3116/4885GABRG2 3629/4885 |
| US-11912704-B2 | Methods and compositions for substituted arylcycloheptane analogs | AHR, HCCS, HMBS | ABCB1 195/4885RAPGEF4 3116/4885GABRG2 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.