Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.36 |
| ▸ | HPGD | P15428 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15349631 | 0.83 | MAPT (0.39) | MAPTHPGDALDH1A1TDP1DRD2 | |
| SCHEMBL9070559 | 0.83 | MAPT (0.39) | MAPTHPGDALDH1A1TDP1DRD2 | |
| SCHEMBL15510613 | 0.79 | ACHE (0.40) | MAPTHPGDALDH1A1TDP1DRD2 | |
| SCHEMBL16111754 | 0.78 | PTGES (0.42) | MAPTHPGDALDH1A1DRD2DRD4 | |
| SCHEMBL23746519 | 0.78 | HPGD (0.33) | MAPTHPGDALDH1A1L3MBTL1DRD2 | |
| SCHEMBL6677387 | 0.77 | HPGD (0.35) | MAPTHPGDALDH1A1NPSR1TDP1 | |
| SCHEMBL24572066 | 0.77 | ALDH1A1 (0.46) | MAPTHPGDALDH1A1NPSR1TDP1 | |
| SCHEMBL20157671 | 0.75 | HTT (0.40) | MAPTHPGDALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL20961724 | 0.75 | NPC1 (0.36) | MAPTHPGDALDH1A1DRD2DRD4 | |
| SCHEMBL8437034 | 0.74 | DRD2 (0.58) | HPGDNPSR1L3MBTL1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033015-A2 | TRANSIENT POLYMER FORMULATIONS, ARTICLES THEREOF, AND METHODS OF MAKING AND USING SAME | GEORGIA TECH RESEARCH CORPORATION (US) | 2020-02-13 | — | — | WO | disclosed |