Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | GUCY1B2 | O75343 | 3/20 | 0.31 |
| ▸ | GUCY1A2 | P33402 | 3/20 | 0.31 |
| ▸ | GUCY1A1 | Q02108 | 3/20 | 0.31 |
| ▸ | GUCY1B1 | Q02153 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170778 | 0.81 | FEN1 (0.36) | SSTR4ALDH1A1HDAC4HCRTR2GUCY1B2 | |
| SCHEMBL2234006 | 0.76 | GUCY1B2 (0.34) | MEN1KMT2ASSTR4ALDH1A1GUCY1B2 | |
| SCHEMBL2317617 | 0.74 | ALDH1A3 (0.33) | ALDH1A1HDAC4PTGDR2TP53 | |
| SCHEMBL2170782 | 0.72 | POLB (0.43) | MEN1KMT2APOLBLMNACYP1A2 | |
| SCHEMBL27872107 | 0.72 | MAOB (0.50) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL4970466 | 0.71 | SCN5A (0.32) | ALDH1A1HDAC4TP53 | |
| SCHEMBL14836967 | 0.71 | SDHB (0.43) | MEN1KMT2AALDH1A1HCRTR2HPGD | |
| SCHEMBL2315731 | 0.71 | TSHR (0.45) | ALDH1A1HCRTR2HPGDMAPTTP53 | |
| SCHEMBL27689604 | 0.69 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL2215750 | 0.68 | PAX8 (0.35) | ALDH1A1HDAC4HCRTR2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351748-A1 | ISOQUINOLINE DERIVATIVE, AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |
| EP-2348018-A1 | HETEROCYCLIC BIARYL DERIVATIVE, AND PDE INHIBITOR COMPRISING SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |