Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.49 |
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20575743 | 0.85 | DPP4 (0.49) | DPP4HTR1AHTR7 | |
| SCHEMBL2355316 | 0.82 | SCN9A (0.52) | SCN9ADPP4HTR1AHTR7FPR2 | |
| SCHEMBL2170169 | 0.75 | SCN9A (0.54) | SCN9ADPP4FPR2 | |
| SCHEMBL2356691 | 0.74 | SCN9A (0.48) | SCN9ADPP4HTR1AHTR7FPR2 | |
| SCHEMBL20575304 | 0.74 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL12836594 | 0.74 | LGMN (0.45) | DPP4 | |
| SCHEMBL12895270 | 0.73 | F2 (0.45) | DPP4 | |
| SCHEMBL12463762 | 0.72 | DPP4 (0.56) | SCN9ADPP4HTR1AHTR7FPR2 | |
| SCHEMBL2172455 | 0.71 | SCN9A (0.60) | SCN9ADPP4HTR1AHTR7FPR2 | |
| SCHEMBL2170987 | 0.71 | CYP2C9 (0.50) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346821-A1 | SPHINGOSINE-1-PHOSPHATE RECEPTOR ANTAGONISTS | Exelixis, Inc. (US) | 2011-07-27 | — | — | EP | disclosed |