Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23506531 | 1.00 | REN (0.45) | RENCTSLCTSBOPRM1CTSK | |
| SCHEMBL21702050 | 0.96 | REN (0.44) | RENCTSLCTSBOPRM1CTSK | |
| SCHEMBL23506412 | 0.91 | CTSL (0.45) | RENCTSLCTSB | |
| SCHEMBL23506296 | 0.91 | CTSL (0.55) | CTSLCTSBCTSK | |
| SCHEMBL21702056 | 0.90 | REN (0.46) | RENCTSLCTSBOPRM1 | |
| SCHEMBL23506236 | 0.90 | REN (0.46) | RENCTSLCTSBOPRM1 | |
| SCHEMBL21702036 | 0.89 | CTSL (0.47) | RENCTSLCTSB | |
| SCHEMBL23506499 | 0.89 | CTSL (0.47) | RENCTSLCTSB | |
| SCHEMBL21702057 | 0.88 | REN (0.44) | RENCTSLCTSBOPRM1 | |
| SCHEMBL23506252 | 0.87 | CTSK (0.51) | CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151387-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | 中国科学院上海药物研究所 | 2021-08-05 | — | — | WO | disclosed |
| WO-2020030143-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 中国科学院上海药物研究所 | 2020-02-13 | — | — | WO | disclosed |