Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23506252 | 0.96 | CTSK (0.51) | CTSLCTSBCTSKTAS1R3TAS1R1 | |
| SCHEMBL23506531 | 0.91 | REN (0.45) | CTSLCTSBCTSK | |
| SCHEMBL21702046 | 0.91 | REN (0.45) | CTSLCTSBCTSK | |
| SCHEMBL23506412 | 0.90 | CTSL (0.45) | CTSLCTSB | |
| SCHEMBL23506250 | 0.89 | CTSK (0.51) | CTSLCTSBCTSKTAS1R3TAS1R1 | |
| SCHEMBL21702050 | 0.87 | REN (0.44) | CTSLCTSBCTSK | |
| SCHEMBL23506329 | 0.87 | CTSK (0.49) | CTSLCTSBCTSK | |
| SCHEMBL21702272 | 0.86 | KLKB1 (0.43) | CTSLCTSB | |
| SCHEMBL23711577 | 0.86 | CTSK (0.50) | CTSLCTSBCTSKTAS1R3TAS1R1 | |
| SCHEMBL23506315 | 0.86 | CTSK (0.50) | CTSLCTSBCTSKTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2023-05-04 | — | — | US | disclosed |
| EP-3835296-A1 | KETOAMIDE COMPOUND AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-06-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133600-A1 | PHARMACEUTICAL USE OF KETOAMIDE-BASED COMPOUND | CTSL, CTSV, CTSS | CTSL 1/4885CTSB 8/4885CTSK 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.