SCHEMBL21702143

SCHEMBL21702143

N#Cc1ccccc1-c1cccc2c1-c1c(-c3ccc(-c4nc(-c5ccccc5)nc(-c5ccccc5)n4)cc3)cccc1C21c2ccccc2Oc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.35
HTT P42858 1/20 0.35
PDK2 Q15119 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
ATR Q13535 1/20 0.32
TRPA1 O75762 3/20 0.32
ALOX15 P16050 2/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ADORA3 P0DMS8 1/20 0.30
TSHR P16473 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA2B P29275 1/20 0.30
ADORA1 P30542 1/20 0.30
EIF4E P06730 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21701708 0.94 PDK2 (0.36) ESR2HTTPDK2GABRG2GABRB3
SCHEMBL21701964 0.94 GABRG2 (0.37) ESR2HTTGABRG2GABRB3GABRA5
SCHEMBL24905756 0.89 HTT (0.33) ESR2HTTPDK2GABRG2GABRB3
SCHEMBL21701686 0.89 KDM4E (0.33) HTTGABRG2GABRB3GABRA5GABRA3
SCHEMBL21701687 0.89 ADORA3 (0.30) ALOX15ADORA3TSHRADORA2AADORA2B
SCHEMBL24905475 0.89 ABCG2 (0.39) HTTPDK2
SCHEMBL24905506 0.88 HTT (0.33) HTTPDK2GABRG2GABRB3GABRA5
SCHEMBL21702147 0.88 MEN1 (0.36) HTTPDK2GABRG2GABRB3GABRA5
SCHEMBL24905416 0.88 PDK2 (0.34) HTTPDK2GABRG2GABRB3GABRA5
SCHEMBL24905505 0.87 PDK2 (0.34) HTTPDK2GABRG2GABRB3GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20200048230-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING SAME LG CHEM, LTD. (KR) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048230-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT INCLUDING SAME CRY1, CRY2, CYP1A1 ESR2 461/4885HTT 3653/4885PDK2 1415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.